Sökning: "personalised medicine"
Visar resultat 1 - 5 av 20 avhandlingar innehållade orden personalised medicine.
1. Study of Resistance in Hepatitis C Virus Prior to Treatment with Direct Acting Antivirals
Sammanfattning : The rapid advancement of Hepatitis C (HCV) treatment presents a great challenge to clinicians in optimising therapy for their patients. Genotype (GT), efficacy, side-effects, drug combinations and treatment durations must be tailored to individual patients, considering comorbidities, degree of fibrosis, adherence and antiviral resistance. LÄS MER
2. Improving prognostication and treatment choices for patients with AML
Sammanfattning : The treatment landscape of the aggressive haematological malignancy acute myeloid leukaemia (AML) has expanded but the prognosis is still unsatisfactory poor. Here, we aimed at improving prognostication and treatment choices in AML by addressing current clinical obstacles to successful AML treatment. LÄS MER
3. Circulating platelets : a novel liquid biopsy source for cancer diagnostics and therapy stratification
Sammanfattning : As conventional tissue biopsies have several drawbacks, much effort has been directed toward the development of minimal-invasive liquid biopsy platforms for detecting and profiling cancer.Platelets are the second most abundant cells in blood and have very versatile functions both in physiological and pathophysiological conditions. LÄS MER
4. Epidemiological aspects of drug-related vitamin D deficiency and osteoporotic fractures
Sammanfattning : Background: Vitamin D deficiency, secondary osteoporosis and low-energy fractures (LEF) as side effects of specific drugs were first described more than half a century ago. These effects are recognized in guidelines where patients prescribed risk drugs are recommended follow-up with testing and supplementation. LÄS MER
5. Methodological approaches towards personalised cancer medicine
Sammanfattning : Despite advances in diagnostics and treatments, many cancer patients have poor survival rates. Tumours develop drug resistance followed by metastasis, and survivors suffer from treatment side-effects. LÄS MER