Sökning: "personalised diagnostics"
Hittade 4 avhandlingar innehållade orden personalised diagnostics.
1. Statistical assessment of genomic variability in tumours and bacterial communities
Sammanfattning : Current high-throughput DNA sequencing technologies have the ability to generate large amounts of high-resolution genomic data. The high dimensionality in combination with the substantial levels of technical errors and biological variability typically present in the data make, however, the analysis challenging. LÄS MER
2. Circulating platelets : a novel liquid biopsy source for cancer diagnostics and therapy stratification
Sammanfattning : As conventional tissue biopsies have several drawbacks, much effort has been directed toward the development of minimal-invasive liquid biopsy platforms for detecting and profiling cancer.Platelets are the second most abundant cells in blood and have very versatile functions both in physiological and pathophysiological conditions. LÄS MER
3. Methodological approaches towards personalised cancer medicine
Sammanfattning : Despite advances in diagnostics and treatments, many cancer patients have poor survival rates. Tumours develop drug resistance followed by metastasis, and survivors suffer from treatment side-effects. LÄS MER
4. Study of Resistance in Hepatitis C Virus Prior to Treatment with Direct Acting Antivirals
Sammanfattning : The rapid advancement of Hepatitis C (HCV) treatment presents a great challenge to clinicians in optimising therapy for their patients. Genotype (GT), efficacy, side-effects, drug combinations and treatment durations must be tailored to individual patients, considering comorbidities, degree of fibrosis, adherence and antiviral resistance. LÄS MER