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Visar resultat 1 - 5 av 100 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Oral delivery of macromolecules formulated with permeation enhancers

   Författare :Staffan Berg; Christel Bergström; Nigel Davies; Andreas Hugerth; David Brayden; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oral peptide delivery; permeation enhancer; sodium caprate; oral drug delivery; intestinal absorption of macromolecules; Biofarmaci; Biopharmaceutics; Galenisk farmaci; Pharmaceutics;

   Sammanfattning : Therapeutic macromolecules including peptides, proteins, and nucleotide-based ones (such as antisense oligonucleotides and RNAs) have great potential as drug candidates. One drawback is that they typically need to be administered parenterally via subcutaneous, intramuscular or intravenous injections. LÄS MER

3. 2. Predicting oral performance of lipid-based formulations using in vitro methods

   Författare :Oliver Hedge; Christel Bergström; Frédéric Carriere; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lipid-based formulation s ; SEDDS; artificial membrane s ; cell monolayer s ; oral drug delivery; lipolysis; permeation; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : Oral administration of drugs is widely considered preferable to other methods by end-users and healthcare providers alike; however, not all drug compounds are inherently suited for it because some molecules are not well-absorbed by the intestine. Good absorption requires both dissolution and permeation. LÄS MER

4. 3. NOx Adsorption and Transport in ZSM-5 Films

   Författare :Indra Perdana; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Wicke-Kallenbach cell; mathematical modelling; NOx adsorption and transport; adsorbed species; ZSM-5 films; permeation;

   Sammanfattning : The present work dealt with a fundamental study of NOx adsorption-desorption and transport in ZSM-5 as films supported on cordierite monolith and as a part of composite membranes. The adsorption-desorption study was focused on developing a mechanistic understanding of NOx adsorption in ZSM-5 films including the effects of counter-ions, Si/Al ratios and film thicknesses on the adsorption. LÄS MER

5. 4. Transport in Oxides Studied by Gas Phase Analysis

   Författare :Qian Dong; Gunnar Hultquist; W.J. Quadakkers; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Gas Phase Analysis; metal; oxide; platinum; vitreous silica; yttria stabilized zirconia; diatomic gas; oxidation; dissociation; permeation; uptake release.; Chemical engineering; Kemiteknik;

   Sammanfattning : The transport in oxides is studied by the use of gas phase analysis (GPA). An experimental method to identify transported species of gases and their contribution to the overall transport of gases in oxides and an experimental method to evaluate the parameters diffusivity, concentration, permeability of gases in oxides and effective pore size in oxides are developed, respectively. LÄS MER

7. 5. Interactions between non-polar surfaces in water: Fokus on talc, pitch and surface roughness effects

   Författare :Viveca Wallqvist; Per Claesson; Janne Laine; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Talc; surface forces; capillary attraction; hydrophobic interaction; pitch control; wetting agent; dispersing agent; adsorption; imbibition; absorption; permeation; atomic force microscopy; colloidal probe; Hamaker constant; surface roughness; nanostructure.; Talk; kapillärattraktion; ytkrafter; hydrofob växelverkan; hartskontroll; vätningsmedel; dispergeringsmedel; adsorption; uppsugning; absorption; permeabilitet; atomkraftsmikroskopi; kolloidal partikel; Hamakerkonstant; ytråhet; nanostrukturerad yta.; Surface and colloid chemistry; Yt- och kolloidkemi; Physical chemistry; Fysikalisk kemi; Chemistry; Kemi;

   Sammanfattning : The aim of this thesis work was to gain understanding of the interactions between talc mineral and surfaces, liquids and chemicals relevant for industrial applications, such as pulp and paper. Talc is used in the pulp and paper industry as a filler pigment, in control of pitch (lipophilic extractives) deposits and as a coating pigment. LÄS MER