Sökning: "periodontitis"

Visar resultat 16 - 20 av 127 avhandlingar innehållade ordet periodontitis.

  1. 16. Genotypic and phenotypic characterization of Porphyromonas gingivalis in relation to virulence

    Författare :Takashi Yoshino; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Porphyromonas gingivalis; Phenotype; Genotype; Virulence; Periodontitis;

    Sammanfattning : The present thesis was designed to increase the knowledge on the role of pathogenic potential of Porphyromonas gingivalis as a putative periodontal pathogen. P. LÄS MER

  3. 17. Complement evasion strategies of human pathogens - the evolutionary arms race

    Författare :Monika Jusko; Malmö Proteinkemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; complement system; pathogen; periodontitis; proteases; immune escape;

    Sammanfattning : Although the complement system, a pivotal component of innate immunty, is centrally involved in host defense against pathogens, its overactivation or deregulation may excessively amplify inflammation and contribute to immunopathology. Periodontitis, an oral infection-driven chronic inflammatory disease, has been linked with complement disruption by periodontal bacteria, resulting in inflammation and pathogenesis. LÄS MER

  4. 18. Interplay between genetics and environment in obesity

    Författare :Dmitry Shungin; Paul W Franks; Eivind Hovig; Umeå universitet; []
    Nyckelord :obesity; GWAS; gene-environment interactions; waist-hip ratio; body mass index; periodontitis; Mendelian randomization; heterogeneity of variance;

    Sammanfattning : Background. Being one of the largest current global health problems, obesity is a result of interplay between genetic and environmental factors. LÄS MER

  5. 19. Vesicle-independent extracellular release and bioactivity of peptidoglycan-associated lipoprotein from Aggregatibacter actinomycetemcomitans

    Författare :Maribasappa Karched; Sirkka Asikainen; Ann-Beth Jonsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptidoglycan-associated lipoprotein; outer membrane proteins; immunoproteomics; periodontitis; cytokines; Aggregatibacter actinomycetemcomitans.; Oral microbiology; Oral mikrobiologi;

    Sammanfattning : Aggregatibacter (Actinobacillus) actinomycetemcomitans is a Gram-negative coccobacillus of the Pasteurellaceae family. It is implicated in periodontitis, a common low-grade bacterial infection, but it can also cause non-oral infections. The main aim of this project was to identify and characterize in A. LÄS MER

  7. 20. Insights into the processes preceding the onset of rheumatoid arthritis

    Författare :Linda Johansson; Solbritt Rantapää Dahlqvist; Mikael Brink; Felipe Andrade; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; pre-symptomatic individuals; autoantibodies; anti-citrullinated protein peptides antibodies; Epstein-barr virus; neutrophil extracellular traps; periodontitis; Porphyromonas gingivalis; receptor activator of nuclear factor kappa-B ligand; reumatologi; rheumatology;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by the production of anti-citrullinated protein antibodies (ACPA) in the majority of all patients and a persistent inflammation in the synovial tissue leading to joint destruction. The aetiology of RA remains to a large extent unknown but is believed to be a complex interplay between genetic, environmental and stochastic factors. LÄS MER