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Visar resultat 1 - 5 av 9 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Perinatal brain injury - markers and mediators. Non-protein-bound iron and pro-inflammatory cytokines in newborn infants and neonatal pigs

    Författare :Karin Sävman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asphyxia; hypoxia; posthemorrhagic ventricular dilatation; preterm; newborn; perinatal; brain; cerebrospinal fluid; cytokines; IL-1ß; IL-6; IL-8; TNF-a; non-protein-bound-iron;

    Sammanfattning : Two groups of newborn infants have an increased risk for perinatal brain injury; preterm infants and term infants subjected to birth asphyxia. Experimental studies indicate that hypoxic-ischemic insults in the perinatal period initiate a secondary neurotoxic cascade including formation of toxic reactive oxygen species as well as an inflammatory response with elevated levels of potentially neurotoxic cytokines. LÄS MER

  2. 2. Management and women's experiences of pregnancies lasting more than 41 gestational weeks

    Författare :Anna Wessberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; experiences; hermeneutic; induction; late-term pregnancy; lifeworld; midwifery; perinatal mortality; ; phenomenology; postterm pregnancy; prenatal care; transition;

    Sammanfattning : It is well known that the risks for complications of both the foetus and the mother increase in post-term pregnancy. To date, there is no uniform worldwide guideline for when to induce a pregnant woman who has passed her estimated due date. Little research has been conducted about women’s own experiences of a pregnancy ≥41 gestational weeks. LÄS MER

  3. 3. Essential fatty acids in the perinatal period. Short and long term effects in a rat model

    Författare :Marina Korotkova; Göteborgs universitet; []
    Nyckelord :EFA; perinatal period; lactation; diet; adipose tissue; leptin; programming;

    Sammanfattning : Nutritional factors during a sensitive perinatal period may lead to developmental adaptations proposed to program for pathological conditions later in life. An adequate supply of essential fatty acids (EFA) during pregnancy and lactation is crucial for optimal fetal and postnatal development. LÄS MER

  4. 4. Neuropsychological consequences at young adult age after cardio-pulmonary resuscitation at birth or being born small-for-gestational age

    Författare :Gerd Viggedal; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; perinatal asphyxia; cardio-pulmonary resuscitation; small-for-gestational age; term infants; young adult; non-disabled; follow-up; cognitive functions; visual attention; auditory attention; education;

    Sammanfattning : The main objective of this thesis was to investigate whether infants resuscitated at birth because of presumed birth asphyxia or born small-for-gestational age without evidence of neurodevelopmental deviations in early childhood, may express cognitive deficits in adulthood when the demands of cognitive and social adaptation increase. Methods: A long-term follow-up was carried out in a group of young adults (n=70), 19-28 years of age, born at Sahlgrens Hospital, Göteborg between 1969 and 1978, requiring cardio-pulmonary resuscitation at birth with a mild or moderate clinical course or born small-for-gestational age (SGA). LÄS MER

  5. 5. Perinatal nicotine exposure. Effects on the defense against hypoxia in lambs

    Författare :Ola Hafström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; carotid body; nicotine; prenatal exposure delayed effects; respiration; respiratory mechanics; sudden infant death; smoking; tobacco;

    Sammanfattning : The aim of the present study was to evaluate whether perinatal nicotine exposure could impair cardiorespiratory defense mechanisms to hypoxia. The rationale for this approach is that exposure to tobacco smoke, particularly before birth, is a risk factor for the sudden infant death syndrome as well as for obstructive airway disease in childhood. LÄS MER