Sökning: "perinatal asphyxia"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden perinatal asphyxia.

1. 1. Perinatal brain injury - markers and mediators. Non-protein-bound iron and pro-inflammatory cytokines in newborn infants and neonatal pigs

   Författare :Karin Sävman; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asphyxia; hypoxia; posthemorrhagic ventricular dilatation; preterm; newborn; perinatal; brain; cerebrospinal fluid; cytokines; IL-1ß; IL-6; IL-8; TNF-a; non-protein-bound-iron;

   Sammanfattning : Two groups of newborn infants have an increased risk for perinatal brain injury; preterm infants and term infants subjected to birth asphyxia. Experimental studies indicate that hypoxic-ischemic insults in the perinatal period initiate a secondary neurotoxic cascade including formation of toxic reactive oxygen species as well as an inflammatory response with elevated levels of potentially neurotoxic cytokines. LÄS MER

3. 2. Cerebral Injury in Perinatal Asphyxia, epidemiological, clinical, neurophysiological and neuromatabolic investigations

   Författare :Kristina Thorngren-Jerneck; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; Neurology; Pediatri; Pediatrics; S100; EEG; CMRgl; cerebral glucose metabolism; FDG-PET; CP; infant; perinatal asphyxia; hypoxia-ischemia;

   Sammanfattning : Perinatal asphyxia with hypoxic ischemic encephalopathy (HIE) is the most important cause of perinatal mortality and cerebral palsy (CP) in infants born at term. The aim of the thesis was to investigate epidemiology of perinatal asphyxia, and to investigate early clinical neurological symptoms after perinatal asphyxia in relation to cerebral glucose metabolism (CMRgl) measured by 18-FDG-PET, neurophysiological function, some biochemical markers, also in relation to long-term outcome. LÄS MER

4. 3. Improving quality of perinatal care through clinical audit : a study from a tertiary hospital in Dar es Salaam, Tanzania

   Författare :Hussein L Kidanto; Lennarth Nyström; Gunilla Lindmark; Siriel Massawe; Geir Jacobsen; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Perinatal mortality; perinatal audit; avoidable factors; anaemia in pregnancy; eclampsia; Epidemiology; Epidemiologi; epidemiologi; Epidemiology;

   Sammanfattning : Perinatal audit has been tested and proved an important tool for reduction of perinatal mortality and assessment of quality of perinatal care. At Muhimbili National Hospital (MNH), a tertiary hospital in Dar es salaam, Tanzania we performed a retrospective cross-sectional study using data from an obstetrics database to classify all perinatal deaths during 1999-2003. LÄS MER

5. 4. Some reproductive health indicators in Ukraine : A study with special emphasis on factors behind induced aboartion and perinatal mortality

   Författare :Iryna Mogilevkina; Sven-Eric Olsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; Ukraine; induced abortion; contraception; perinatal mortality; self-completion survey; perinatal audit; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; Obstetrics and Gynaecology; obstetrik och gynekologi;

   Sammanfattning : Objectives: To study indicators specifically reflecting the reproductive health of Ukrainian women and to analyse factors behind the indicators. Methods: Induced abortion and maternal mortality were studied in some countries/regions of the former Soviet Union, using official statistics. LÄS MER

7. 5. Targeting apoptosis-inducing factor as a novel therapeutic strategy for preventing perinatal brain injury

   Författare :Juan Rodriguez; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AIF; neonatal; mouse; hypoxia-ischemia; AIF CypA complex; apoptosis; asphyxia; CHCHD4;

   Sammanfattning : Perinatal complications such as asphyxia can cause brain injuries that are often associated with subsequent neurological deficits. The mechanisms of perinatal brain injury are not fully understood, but mitochondria play a prominent role, not only due to their central function in metabolism, but also because many proteins with apoptosisrelated functions are located in the mitochondrion. LÄS MER