Sökning: "per enblad"
Visar resultat 16 - 20 av 20 avhandlingar innehållade orden per enblad.
16. Aspects on Mechanisms, Treatment and Outcome in Severe Traumatic Brain Injury
Sammanfattning : Traumatic brain injury (TBI) is a leading cause for mortality and morbidity worldwide. The primary injury has great impact on patient outcome and cannot be cured, but attentive neurointensive care (NIC) may reduce detrimental secondary brain injuries and is the focus of this thesis. LÄS MER
17. Surgical Outcomes in Sagittal Craniosynostosis
Sammanfattning : The overarching aim of this thesis was to increase the understanding of patient and treatment related factors behind the variability in morphological outcomes seen in nonsyndromic sagittal craniosynostosis. There is a lack of knowledge regarding patient related predictors for the variability in outcomes, and consensus has yet to be reached regarding best practice with respect to surgical technique for the treatment of sagittal craniosynostosis. LÄS MER
18. Neurointensive Care of Children with Severe Traumatic Brain Injury : Studies of barbiturate coma treatment, intracranial compliance, pressure autoregulation and optimal cerebral perfusion pressure
Sammanfattning : Traumatic brain injury (TBI) is among the most common causes of death and acquired disability during childhood. Management guidelines for pediatric patients are usually extrapolated from adults. Specific pediatric studies are warranted to improve the TBI management in children. LÄS MER
19. On the pathophysiology of idiopathic adult hydrosephalus syndrome : energy metabolism, protein patterns, and intracranial pressure
Sammanfattning : The symptoms in Idiopathic Adult Hydrocephalus Syndrome (IAHS) – gait disturbance, incontinence, and cognitive deficit – correlate anatomically to neuronal dysfunction in periventricular white matter. The pathophysiology is considered to include a cerebrospinal fluid (CSF) hydrodynamic disturbance, including pressure oscillations (“B waves”), in combination with cerebrovascular disease. LÄS MER
20. DNA Damage Response of Normal Epidermis in the Clinical Setting of Fractionated Radiotherapy : Evidence of a preserved low-dose hypersensitivity response
Sammanfattning : Investigations of DNA damage response (DDR) mechanisms in normal tissues have implications for both cancer prevention and treatments. The accumulating knowledge about protein function and molecular markers makes it possible to directly trace and interpret cellular DDR in a tissue context. LÄS MER