Sökning: "peptidoglycan"

Visar resultat 1 - 5 av 53 avhandlingar innehållade ordet peptidoglycan.

  1. 1. Peptidoglycan Recognition Proteins : Major Regulators of Drosophila Immunity

    Författare :Peter Mellroth; Håkan Steiner; Julien Royet; Stockholms universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Innate immunity; peptidoglycan recognition protein; PGRP; Toll; Imd; Drosophila immunity; Microbiology and immunology; Mikrobiologi och immunologi;

    Sammanfattning : All eukaryotic organisms have an innate immune system characterized by germ-line encoded receptors and effector molecules, which mediate detection and clearance of microbes such as bacteria, fungi, and parasites. VertebrateDrosophila as a genetically tractable organism with a This thesis concerns the peptidoglycan recognition protein (PGRP) gene family in the fruit fly. LÄS MER

  3. 2. Uncovering novel cell wall chemistries in gram negative bacteria : from development or dedicated peptidoglycan chemometric tools to functional genomics

    Författare :Akbar Espaillat; Felipe Cava; Sun Nyunt Wai; Waldemar Vollmer; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bacteria; cell wall; peptidoglycan; peptidoglycan variations; D-amino acids; molekylärbiologi; Molecular Biology;

    Sammanfattning : Bacteria are surrounded by an external cell wall whose main component is a polymeric net-like structure called the peptidoglycan (PG) or murein sacculus. PG plays crucial roles in bacterial physiology (eg morphogenesis, growth fitness and regulation of innate immunity). LÄS MER

  4. 3. Peptidoglycan recognition proteins in Drosophila melanogaster

    Författare :Thomas Werner; Dan Hultmark; Bruno Lemaitre; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Drosophila; PGRP; peptidoglycan; pattern recognition; imd; Relish; isoform; RNAi; mbn-2; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The fruit fly Drosophila melanogaster is an excellent model organism to study the innate immune response, because insects and mammals share conserved features regarding the recognition and destruction of microorganisms and Drosophila is easily accessible to genetic manipulation. In my present study, I identified a new family of pattern recognition molecules for bacterial peptidoglycan in Drosophila, the Peptidoglycan Recognition Proteins (PGRP). LÄS MER

  5. 4. On the role of penicillin-binding protein SpoVD in endospore cortex assembly

    Författare :Ewa Bukowska-Faniband; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; sporulation; cortex; Bacillus subtilis; penicillin-binding proteins; SpoVD; peptidoglycan;

    Sammanfattning : Bacteria of the genera Bacillus and Clostridium can form endospores as a strategy to survive unfavourable environmental conditions. Endospore formation involves synthesis of cortex, a thick layer of modified peptidoglycan that surrounds the spore. LÄS MER

  7. 5. Staphylococcal induced inflammatory response in human monocytes: Analysis of factors involved

    Författare :Eva Mattsson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; interleukin-6; interleukin-beta; TNF-alfa; teichoic acid; Staphylococcus epidermidis; peptidoglycan; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Purified bacterial cell wall components peptidoglycan and teichoic acid were isolated from staphylococcal species S. aureus and/or S. epidermidis and tested for their ability to induce cytokine release from plastic-adherent human monocytes. LÄS MER