Sökning: "peptides"

Visar resultat 6 - 10 av 1142 avhandlingar innehållade ordet peptides.

  1. 6. Cell-penetrating peptides : Uptake mechanism and the role of receptors

    Författare :Henrik Helmfors; Ülo Langel; Hanne Mørck Nielsen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Genes are the major regulators of biological processes in every living thing. Problems with gene regulation can cause serious problems for the organism; for example, most cancers have some kind of genetic component. Regulation of biological processes using oligonucleotides can potentially be a therapy for any ailment, not just cancer. LÄS MER

  3. 7. Microgels as Carriers for Antimicrobial Peptides : Surface-bound microgels, and factors affecting peptide interactions

    Författare :Lina Nyström; Martin Malmsten; Per Hansson; L. Andrew Lyon; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Antimicrobial peptides; Biomaterial coating; Drug delivery; Host defence peptides; Microgels; pH-responsive; Surface-bound; Pharmaceutical Physical Chemistry; Farmaceutisk fysikalisk kemi;

    Sammanfattning : With a growing number of multi-resistant bacteria against conventional antibiotics, there is an urgent need to identify new antimicrobial therapeutics. One example that has gained considerable interest is antimicrobial peptides (AMPs). LÄS MER

  4. 8. CELL PENETRATING PEPTIDES : CHEMICAL MODIFICATION AND FORMULATION DEVELOPMENT

    Författare :Kariem Ezzat; Ülo Langel; Astrid Gräslund; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Sammanfattning : Cell penetrating peptides (CPPs) have been extensively studied and exploited as drug delivery vectors for a wide variety of therapeu-tic cargos. However, several issues remain to be addressed regarding the enhancement of their efficiency and stability. LÄS MER

  5. 9. Cell penetrating peptides : mechanisms and applications

    Författare :Mattias Hällbrink; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  7. 10. Development of antimicrobial peptides : Methodological aspects, design, synthesis and evaluation of a new class of antimicrobial peptides

    Författare :Marie Danielsson; Anders Undén; Maria Kempe; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : A new protective group for the indole nitrogen of the amino acid tryptophan, the Boc-sarcosinoyl-sarcosinolyl (Boc-Sar-Sar) is described. This protective group shows good stability to the reaction conditions used in solid phase peptide synthesis and can be incorporated into the peptide as Fmoc-Trp(Boc-Sar-Sar)-OH. LÄS MER