Sökning: "penetratin"
Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet penetratin.
1. Studies of the interaction of penetratin with phospholipid vesicles
Sammanfattning : .... LÄS MER
2. Interactions of the Cell-Penetrating Peptide Penetratin with Model Membranes and Live Cells
Sammanfattning : The delivery of large, hydrophilic molecules, such as proteins and oligonucleotides, to the cytoplasm and nucleus of cells is problematic due to their generally low plasma membrane permeability. With the identification of a number of cell-penetrating peptides, capable of mediating non-endocytotic, intracellular delivery of macromolecular cargos, this obstacle now seems surmountable. LÄS MER
3. Cell-Penetrating Penetratin Peptides - Mechanistic Studies on Uptake Pathways and DNA Delivery Efficiency
Sammanfattning : Delivery of gene-targeted drugs is limited by the inherently poor capacity of nucleic acids to overcome the membrane barrier of the cell, and development of vectors that can promote uptake is therefore crucial. Cell penetrating peptides (CPPs) have emerged as promising vector candidates due to their ability to deliver a wide range of macromolecular cargos into cells. LÄS MER
4. Polarized-light spectroscopy of membrane and DNA bound molecules
Sammanfattning : .... LÄS MER
5. Structure and Dynamics of Membrane Associated Peptides
Sammanfattning : The peptide-membrane interaction is a key element for many biological functions, from cell signaling to cell internalization. In this thesis the peptide-membrane interaction of six different peptides have been studied with respect to their structure, membrane location and dynamics with spectroscopic methods. LÄS MER