Sökning: "pattern recognition proteins"

Visar resultat 1 - 5 av 45 avhandlingar innehållade orden pattern recognition proteins.

  1. 1. Peptidoglycan recognition proteins in Drosophila melanogaster

    Detta är en avhandling från Umeå : Umeå centrum för molekylär patogenes (UCMP) (Medicinska fakulteten)

    Författare :Thomas Werner; Umeå universitet.; [2004]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Drosophila; PGRP; peptidoglycan; pattern recognition; imd; Relish; isoform; RNAi; mbn-2; Molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The fruit fly Drosophila melanogaster is an excellent model organism to study the innate immune response, because insects and mammals share conserved features regarding the recognition and destruction of microorganisms and Drosophila is easily accessible to genetic manipulation. In my present study, I identified a new family of pattern recognition molecules for bacterial peptidoglycan in Drosophila, the Peptidoglycan Recognition Proteins (PGRP). LÄS MER

  2. 2. Automated Tissue Image Analysis Using Pattern Recognition

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Jimmy Azar; Uppsala universitet.; Uppsala universitet.; [2014]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; tissue image analysis; pattern recognition; digital histopathology; immunohistochemistry; paired antibodies; histological stain evaluation; Computerized Image Processing; Datoriserad bildbehandling;

    Sammanfattning : Automated tissue image analysis aims to develop algorithms for a variety of histological applications. This has important implications in the diagnostic grading of cancer such as in breast and prostate tissue, as well as in the quantification of prognostic and predictive biomarkers that may help assess the risk of recurrence and the responsiveness of tumors to endocrine therapy. LÄS MER

  3. 3. Recognition by leukocyte formyl peptide receptors. Promiscuous binding or pattern recognition?

    Detta är en avhandling från Göteborg

    Författare :Johan Bylund; Göteborgs universitet.; Gothenburg University.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; chemoattractant; FPRL1; NADPH-oxidase; LPS; priming; subcellular organelles; human; murine;

    Sammanfattning : Neutrophil granulocytes play an important role in the early stages of microbial infection. The neutrophils have to leave the blood stream and migrate out into the tissue where they phagocytose microbes and cell debris from damaged host tissues. LÄS MER

  4. 4. Innate Immune Proteins in a Crustacean Pacifastacus leniusculus

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Chenglin Wu; Uppsala universitet.; [2011]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 2-DE; hematopoiesis; marker protein; melaniztion inhibiting protein; proPO-system; pattern recognition protein; PGN; ficolin-like protein; NATURAL SCIENCES Biology Cell and molecular biology Immunology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Immunologi; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Sammanfattning : Hemocytes (blood cells) are important in the immune defense against pathogens in invertebrates. In crusteacean, the hemocytes and plasma components mount a strong innate immune response against different pathogens including bacteria and virus. LÄS MER

  5. 5. A Novel Route for Construction of Multipurpose Receptors through Chemical Modification of Glutathione Transferases

    Detta är en avhandling från Institutionen för teknik och naturvetenskap

    Författare :Johan Viljanen; Linköpings universitet.; Linköpings universitet.; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Human GST A1-1; site-specific covalent modification; tyrosine 9; lysine 216; methionine 208; multipurpose receptor; pattern recognition; protein purification; NATURAL SCIENCES Chemistry; NATURVETENSKAP Kemi;

    Sammanfattning : This thesis describes how the human Alpha class glutathione transferase (GST) A1-1 can be reprogrammed either to function as a multipurpose biosensor for detection of small molecule analytes, or as a handle providing for more efficient protein purification.A novel, user-friendly, and efficient method for site-specific introduction of functional groups into the active site of hGST A1-1 is the platform for these achievements. LÄS MER