Sökning: "pattern recognition protein"

Visar resultat 1 - 5 av 61 avhandlingar innehållade orden pattern recognition protein.

  1. 1. Innate Immune Proteins in a Crustacean Pacifastacus leniusculus

    Författare :Chenglin Wu; Irene Söderhäll; petr Kopácek; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; 2-DE; hematopoiesis; marker protein; melaniztion inhibiting protein; proPO-system; pattern recognition protein; PGN; ficolin-like protein; Immunology; Immunologi; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Sammanfattning : Hemocytes (blood cells) are important in the immune defense against pathogens in invertebrates. In crusteacean, the hemocytes and plasma components mount a strong innate immune response against different pathogens including bacteria and virus. LÄS MER

  3. 2. Peptidoglycan recognition proteins in Drosophila melanogaster

    Författare :Thomas Werner; Dan Hultmark; Bruno Lemaitre; Umeå universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Drosophila; PGRP; peptidoglycan; pattern recognition; imd; Relish; isoform; RNAi; mbn-2; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The fruit fly Drosophila melanogaster is an excellent model organism to study the innate immune response, because insects and mammals share conserved features regarding the recognition and destruction of microorganisms and Drosophila is easily accessible to genetic manipulation. In my present study, I identified a new family of pattern recognition molecules for bacterial peptidoglycan in Drosophila, the Peptidoglycan Recognition Proteins (PGRP). LÄS MER

  4. 3. Pattern-recognition receptors in airway inflammation

    Författare :Anna-Karin Ekman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Airway inflammation is a defining feature of allergic rhinitis and asthma. Bacterial and viral infections are known to cause exacerbations of both diseases, but knowledge about the mechanisms involved is limited. LÄS MER

  5. 4. A Novel Route for Construction of Multipurpose Receptors through Chemical Modification of Glutathione Transferases

    Författare :Johan Viljanen; Bengt Harald Jonsson; Kerstin Broo; Sophia Hober; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Human GST A1-1; site-specific covalent modification; tyrosine 9; lysine 216; methionine 208; multipurpose receptor; pattern recognition; protein purification; Chemistry; Kemi;

    Sammanfattning : This thesis describes how the human Alpha class glutathione transferase (GST) A1-1 can be reprogrammed either to function as a multipurpose biosensor for detection of small molecule analytes, or as a handle providing for more efficient protein purification.A novel, user-friendly, and efficient method for site-specific introduction of functional groups into the active site of hGST A1-1 is the platform for these achievements. LÄS MER

  7. 5. Recognition by leukocyte formyl peptide receptors. Promiscuous binding or pattern recognition?

    Författare :Johan Bylund; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :neutrophils; chemoattractant; FPRL1; NADPH-oxidase; LPS; priming; subcellular organelles; human; murine;

    Sammanfattning : Neutrophil granulocytes play an important role in the early stages of microbial infection. The neutrophils have to leave the blood stream and migrate out into the tissue where they phagocytose microbes and cell debris from damaged host tissues. LÄS MER