Sökning: "pattern modifications"

Visar resultat 6 - 10 av 63 avhandlingar innehållade orden pattern modifications.

  1. 6. Maintenance of neuronal identity and function

    Författare :Konstantinos Toskas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neurons in the CNS acquire specific characteristics throughout development and maintain them for the entire lifespan. Instructive regulation of the transcription machinery ensures the acquisition of identity by spatiotemporal patterns of transcription factor expression. LÄS MER

  3. 7. Mechanisms Underlying Intensive Care Unit Muscle Wasting : Intervention Strategies in an Experimental Animal Model and in Intensive Care Unit Patients

    Författare :Monica Llano-Diez; Lars Larsson; Marco Sandri; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute quadriplegic myopathy; intensive care unit; myosin; regulation of contraction; muscle atrophy; mechanical loading; mobilization; Clinical Neurophysiology; Klinisk neurofysiologi;

    Sammanfattning : Critically ill patients admitted to the intensive care unit (ICU) commonly develop severe muscle wasting and weakness and consequently impaired muscle function. This not only delays respirator weaning and ICU discharge, but has deleterious effects on morbidity, mortality, financial costs, and quality of life of survivors. LÄS MER

  4. 8. DNA adductomics: Method development and integration in biological effect monitoring

    Författare :Giulia Martella; Elena Gorokhova; Hitesh V. Motwani; Brita Sundelin; Gunnar Boysen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA adducts; Nucleic acids; High-resolution mass spectrometry; Data-independent acquisition; Biological effect monitoring; Environmental contaminants; Biomarkers; Amphipods as sentinel species; Environmental Sciences; miljövetenskap;

    Sammanfattning : Environmental omics can provide informative biomarkers for identifying pathologies or physiological responses to environmental change. Nucleic acid adductomics, one of the newest omics techniques, is particularly well suited for assessing exposure and effects of environmental contaminants because the technique can capture modifications at the (epi)genome level. LÄS MER

  5. 9. Oxidized Cladophora nanocellulose derivatives : Functionalization towards biocompatible materials

    Författare :Igor Rocha; Jonas Lindh; Natalia Ferraz; Albert Mihranyan; Maria Strömme; Eva Malmström Jonsson; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Cladophora nanocellulose; TEMPO oxidation; periodate oxidation; sulfonation; cellulose beads; surface properties; biomaterials; cell studies; hemocompatibility;

    Sammanfattning : Nanocellulose is a promising candidate for biomedical applications because of its enhanced mechanical properties, increased surface area and greater porosity compared to bulk cellulose.This thesis investigates the functionalization of Cladophora nanocellulose and evaluates the influence of these modifications on physicochemical properties and biocompatibility of the material. LÄS MER

  7. 10. Towards a Low Latency Internet: Understanding and Solutions

    Författare :Mohammad Rajiullah; Anna Brunstrom; Pasi Sarolahti; Karlstads universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; latency; traffic classification; slow-start; TCP; SCTP; PR-SCTP; NR-SACKs; event logging; performance evaluation; Datavetenskap; Computer Science;

    Sammanfattning : Networking research and development have historically focused on increasing network throughput and path resource utilization, which particularly helped bulk applications such as file transfer and video streaming. Recent over-provisioning in the core of the Internet has facilitated the use of interactive applications like interactive web browsing, audio/video conferencing, multi- player online gaming and financial trading applications. LÄS MER