Sökning: "patologi Patologi"

Visar resultat 16 - 20 av 487 avhandlingar innehållade orden patologi Patologi.

1. 16. Leucine-rich repeats and immunoglobulin-like domain (LRIG) proteins : possible prognostic markers in vulvar squamous cell carcinoma, endometrial carcinoma, and oropharymgeal squamous cell carcinoma

   Författare :Husam Oda; David Lindquist; Eva Lundin; Ulrika Ottander; Kristina Stefansson; Kate Cuschieri; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vulvar squamous cell carcinoma; endometrial carcinoma; oropharyngeal squamous cell carcinoma; LRIG1-3; HPV; LMO7; HPV-driven; non-HPV-driven; prognosis; overall survival; disease-free survival; p53; Ki-67; CD8 TILs; CD44.; Pathology; patologi;

   Sammanfattning : The human leucine-rich repeats and immunoglobulin-like domain (LRIG) gene family comprises three genes, LRIG1, LRIG2 and LRIG3, which encode the LRIG1, LRIG2 and LRIG3 proteins, respectively. Previous stidies have revealed the different prognostic roles of these proteins in different cancers, and it has been shown that LRIG1 functions as a tumour suppressor in certain cancers via its negative regulation of several receptor tyrosine kinases. LÄS MER

3. 17. Early effects of castration therapy in non-malignant and malignant prostate tissue

   Författare :Nina Ohlson; Pernilla Wikström; Anders Bergh; Pär Stattin; Marja Nevalainen; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; human biopsies; androgen ablation; stroma; epithelium; micro-dissection; PSA; IGF-1; IGF-R1; AR; Pathology; Patologi;

   Sammanfattning : Early Effects of Castration Therapy in Non-malignant and Malignant Prostate Tissue BACKGROUND. Androgen ablation, the standard treatment for advanced prostate cancer, results in increased apoptosis, decreased cell proliferation and subsequent involution of the prostate gland. LÄS MER

4. 18. Squamous cell carcinoma of the oral tongue : studies of biomarkers connected to human papillomavirus infection, epithelial to mesenchymal transition and locoregional metastatis

   Författare :Nicola Sgaramella; Karin Nylander; Karin Danielsson; Giuseppe Colella; Robin Fåhraeus; Lorenzo Lo Muzio; George Sekine; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; squamous cell carcinoma oral tongue; p16; HPV; podoplanin; E-cadherin; patologi; Pathology;

   Sammanfattning : Background: Oral Tongue Squamous Cell Carcinoma (OTSCC) is the most frequent and aggressive carcinoma in the head and neck region. Its incidence has increased during the last decades, especially in young patients (≤40 years) mainly female. LÄS MER

5. 19. Telomere length : dynamics and role as a biological marker in malignancy

   Författare :Ulrika Svenson; Göran Roos; Uwe Martens; Umeå universitet; []
   Nyckelord :Telomere length; peripheral blood; immune cells; breast cancer; renal cell carcinoma; biological marker; patologi; Pathology;

   Sammanfattning : Telomeres are protective structures at the end of our chromosomes, composed of multiple repeats of the DNA sequence TTAGGG. They are essential for maintaining chromosomal stability by preventing damage and degradation of the chromosome ends. LÄS MER

7. 20. Analysis of Sun-Damaged Skin and Epidermal p53 Clones

   Författare :Helena Bäckvall; Nicole Basset-Seguin; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Patologi; Pathology; Patologi; Pathology; patologi;

   Sammanfattning : Sun-damaged skin is a relevant target tissue for studying the development of skin cancer. The aim of the present study was to investigate the epidermal response to ultraviolet radiation (UVR) in human skin in vivo and in vitro and to explore the mutagenic effect of UVA. LÄS MER