Sökning: "patofysiologi"

Visar resultat 1 - 5 av 17 avhandlingar innehållade ordet patofysiologi.

1. 1. Identification of pathophysiological and prognostic biomarkers in different types of myocardial infarction

   Författare :Marcus Hjort; Bertil Lindahl; Kai M. Eggers; Helge Rørvik Røsjø; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; myocardial infarction; biomarker; pathophysiology; prognosis; MINOCA; STEMI; NSTEMI; hjärtinfarkt; biomarkör; patofysiologi; prognos; MINOCA; STEMI; NSTEMI; Cardiology; Kardiologi;

   Sammanfattning : The pathophysiological mechanisms of myocardial infarction (MI) with non-obstructive coronary arteries (MINOCA) are largely unknown. Analogous, differences in pathobiology between ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) are incompletely understood. LÄS MER

3. 2. Abdominal Aortic Aneurysm : Molecular Imaging Studies of Pathophysiology

   Författare :Gustaf Tegler; Anders Wanhainen; Martin Björck; Jens Sörensen; Lars Norgren; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Abdominal aortic aneurysm; AAA; Positron emission tomography; PET; Molecular Imaging; Pathophysiology; Autoradiography; Angiogenesis; integrin alphaVbeta3; FDG; 18F-FDG; 11C-PK11195; 11C-D-deprenyl; [18F]fluciclatide; Fluciclatide; Bukaortaaneurysm; Molekylär bilddiagnostik; Patofysiologi; PET; Autoradiografi; Angiogenes; Surgery; Kirurgi; Medicinsk radiofysik; Medical Radiophysics;

   Sammanfattning : The pathological process behind abdominal aortic aneurysm (AAA) formation is poorly understood and difficult to study. The aim of the thesis was to study the pathophysiology of AAA formation with positron emission tomography (PET) technology, a molecular imaging technique, allowing in vivo studies of pathophysiological changes. LÄS MER

4. 3. Striatal pathways in dyskinesia and dystonia

   Författare :Laura Andreoli; Basala gangliernas patofysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Striatum; Dystonia; L-DOPA-induced dyskinesia; DREADD; Mouse model; Dopamine; dopamine receptor;

   Sammanfattning : Purposeful and well-coordinated movements depend on the control exerted by dopamine (DA) on the basal ganglia (BG) network. Accordingly, dysfunctions or lesions of the dopaminergic system in the BG can result in an overall poverty and slowness of movement, cardinal features of Parkinson´s disease (PD), or in dyskinesias, exaggerated and involuntary movements resulting from L-DOPA pharmacotherapy. LÄS MER

5. 4. Endogenous and treatment-induced neuroplasticity in mouse models of Parkinson's disease

   Författare :Francesco Bez; Basala gangliernas patofysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Parkinson´s disease (PD) is an age-related neurodegenerative disorder characterized by a loss of nigral dopamine (DA) neurons that project their axons to the striatum. Striatal DA depletion causes the typical motor symptoms of PD. LÄS MER

7. 5. Striatal adaptations in experimental parkinsonism and L-DOPA-induced dyskinesia

   Författare :Tim Fieblinger; Basala gangliernas patofysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Striatum; Parkinson’s disease; L-DOPA-induced dyskinesia; ERK1 2; mGluR5; homeostatic plasticity; SPN; 2‑Photon microscopy;

   Sammanfattning : Parkinson’s disease (PD) is a neurodegenerative disorder, characterized by the loss of dopamine (DA) producing neurons in the substantia nigra pars compacta (SNc), resulting in typical motor symptoms. DA replacement with L-DOPA is the standard therapy for PD. LÄS MER