Sökning: "pathways of infections"

Visar resultat 1 - 5 av 122 avhandlingar innehållade orden pathways of infections.

  1. 1. Imported infections’ importance : global change driving Dengue dynamics

    Författare :Mikkel B. Quam; Joacim Rocklöv; Annelies Wilder-Smith; Eduardo Massad; Dave D. Chadee; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dengue; Zika; Vector-borne Disease; Aedes; Global Change; Climate Change; Viral Evolution; Phylogenetics; Travel; Interconnectivity; Disease Modeling; Madeira; Italy; Japan; Europe;

    Sammanfattning : Background Dengue is a significant problem of international health concern. According to the World Health Organization in 2012, globally, dengue is “the most important mosquito borne viral disease” with incidence 30 higher than it had been 50 years ago. LÄS MER

  3. 2. Host control of intracellular bacterial infections

    Författare :Emma Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Listeria monocytogenes; CD44; flagellin; Chlamydia pneumoniae; TLR; NOD; IFNalpha beta; IFN-gamma;

    Sammanfattning : In this thesis various immune mechanisms regulating control of infections with the intracellular bacteria Listeria monocytogenes and Chlamydia pneumoniae have been studied. These bacteria infect macrophages in which they can successfully grow. However, macrophages are potent killers of intracellular bacteria. LÄS MER

  4. 3. Role of alveolar epithelial cells in macrophage responses against mycobacterial infections

    Författare :Olga Daniela Chuquimia Flores; Carmen Fernández; Diana Boraschi; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lung; alveolar epithelial cells; macrophages; AEC-derived media; control of intracellular bacterial growth; mycobacterial infections; immunologi; Immunology;

    Sammanfattning : This thesis aimed to investigate the role of alveolar epithelial cells (AEC) on immune responses against mycobacterial infections, specifically, the role of AEC in modulating macrophage functions through the secretion of broad variety of factors.In paper I, we compared murine AEC with interstitial macrophages (PuM) in their ability to take up and control mycobacterial growth and their capacity as antigen-presenting cells. LÄS MER

  5. 4. Diagnosis and management of periprosthetic joint infections

    Författare :Karin Svensson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; periprosthetic joint infection; arthroplasty surgery;

    Sammanfattning : Periprosthetic joint infection (PJI) is a severe complication to hip and knee arthroplasty surgery. In the light of its devastating implications for the affected patient, its great economic impact on the health care system and the increasing antimicrobial resistance, it is important to develop efficient diagnostic methods, identify optimal treatment pathways and improve the care for patients. LÄS MER

  7. 5. Role of SOCS proteins during mycobacterial infections

    Författare :Berit Carow; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mycobacterium tuberculosis is the world’s most successful bacterial killer. During infection, mycobacteria reside inside host cells encapsulated within a granuloma structure in the latent, asymptomatic phase of infection. Only 10% of latently infected develop active, infectious tuberculosis months or years after the initial infection. LÄS MER