Sökning: "pathogen diagnostics"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden pathogen diagnostics.

  1. 1. Nucleic Acid Based Pathogen Diagnostics

    Författare :Michael S. Akhras; Pål Nyrén; Nader Pourmand; Mats Nilsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; pathogen diagnostics; antibiotic resistance; connector inversion probes CIPer ; human papillomavirus HPV ; genotyping; global health diagnostic forum; molecular inversion probe MIP ; neisseria gonorrhoeae; padlock probes; pyrosequencing; Biochemistry; Biokemi;

    Sammanfattning : Pathogenic organisms are transmitted to the host organism through all possible connected pathways, and cause a myriad of diseases states. Commonly occurring curable infectious diseases still impose the greatest health impacts on a worldwide perspective. LÄS MER

  3. 2. Molecular diagnostics of infectious diseases

    Författare :Malin Nygren; KTH; []
    Nyckelord :;

    Sammanfattning : In DNA-based diagnostics, the polymerase chain reaction(PCR) is the most widely used DNA amplification method. Toenable both sensitive and specific detection of agents causinginfectious diseases, the PCR needs to becombined with methodsto prepare the clinical sample containing the genetic materialof the pathogen. LÄS MER

  4. 3. Magnetic Nanoparticle Based Biosensors for Pathogen Detection and Cancer Diagnostics

    Författare :Bo Tian; Mattias Strömberg; Peter Svedlindh; Hakho Lee; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Magnetic biosensors; magnetic nanoparticles; homogeneous assays; volumetric sensing; Engineering Science with specialization in Solid State Physics; Teknisk fysik med inriktning mot fasta tillståndets fysik;

    Sammanfattning : This thesis describes several magnetic nanoparticle (MNP)-based biosensing strategies which take advantage of different magnetic sensors, molecular tools and nanotechnologies. Proposed biosensors can be classified into three groups, i.e., immunoassay-based, molecular amplification-based, and nanoparticle assembly-based. LÄS MER

  5. 4. A holistic approach to host-pathogen interactions : Detecting the large to unravel the small

    Författare :Kristoffer Sjöholm; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mass spectromery; Proteomics; Host-pathogen interactions; Sepsis;

    Sammanfattning : Sepsis is one of the leading causes of mortality and morbidity in the world, and is an overreaction by the immune system due to pathogen invasion of the bloodstream. The interactions, particularly the protein interactions, between the host and pathogen are fundamental for the outcome of the disease. LÄS MER

  7. 5. Microfluidic blood sample preparation for rapid sepsis diagnostics

    Författare :Jonas Hansson; Hjalmar Brismar; Aman Russom; Fredrik Nikolajeff; KTH; []
    Nyckelord :3D fluidic networks; bacteria isolation; inertial microfluidics; lab-on-chip; microfluidics; particle filtration; PDMS membrane; selective cell lysis. sepsis;

    Sammanfattning : Sepsis, commonly referred to as blood poisoning, is a serious medical condition characterized by a whole-body inflammatory state caused by microbial infection. Rapid treatment is crucial, however, traditional culture-based diagnostics usually takes 2-5 days. LÄS MER