Sökning: "patchclamp"
Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet patchclamp.
1. Effects pf hypoxia and antiepileptic drugs of electrophysiological properties of CA1 neurons in hippocampus
Sammanfattning : This thesis is based on three experimental studies (I-III) of CA1 hippocampal neurons in rat brain slices, where the electrophysiological properties are examined with patch clamp technique under hypoxic conditions and during treatment with antiepileptic drugs, respectively. The cells were visualized and identified in the slice by means of infrared differential interference contrast (IR-DIC) video microscopy and the experiments were carried out at room temperature (22-25 ºC). LÄS MER
2. Neutrophil phagocytosis and secretion : The role of calcium and the cytoskeleton
Sammanfattning : Neutrophils assure rapid removal of bacteria by a variety of processes. They crawl out of the vessels, phagocytose the bacteria and kill them by secretion of bactericidal substances and production of oxidative metabolites. LÄS MER
3. Adult human neural stem cells : properties in vitro and as xenografts in the spinal cord
Sammanfattning : Though the presence of stem cells in the adult human brain has been presented earlier, much has yet to be discovered about these cells. However, the mere potential of these cells has had a significant impact of how we today evaluate the regenerative capacity of the central nervous system and, importantly, on the possible means for science to provide insights in neural repair. LÄS MER
4. Mechanisms of type 1 diabetic serum-induced hyperactivation of CaV1 channels in the pancreatic β cell
Sammanfattning : The pancreatic β cell relies on appropriate Ca2+ entry through voltage-gated calcium (CaV) channels to accomplish its unique function insulin secretion and to guarantee its viability. Well-regulated β cell CaV channels are critical to ensure adequate functional β cell mass, thereby maintaining adequate insulin release and glucose homeostasis in the body. LÄS MER
5. A gastight microfluidic system combined with optical tweezers and optical spectroscopy for electrophysiological investigations of single biological cells
Sammanfattning : Stroke affects around 20 million people around the world every year. Clinically, stroke is a result of brain damage due to the shortage of oxygen delivered to the nerve cells. To minimize suffering and costs related to the disease, extensive research is performed on different levels. LÄS MER