Sökning: "parasite resistance"

Visar resultat 21 - 25 av 56 avhandlingar innehållade orden parasite resistance.

  1. 21. Search for genetic determinants of Plasmodium falciparum malaria drug resistance in vitro and in vivo

    Författare :Aminatou Kone; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malaria remains the most deadly disease in the world with nearly 627 000 deaths and more than 200 million new clinical cases every year, the large majority occurring in sub Saharan Africa children aged < 5 years. This represents anyway a significant decrease as compared with the situation in the start of the Millennium. LÄS MER

  3. 22. Factors Influencing Evolution to Antimalarial Drug Resistance in Plasmodium falciparum in Sudan and The Gambia

    Författare :Amany Kheir; Göte Swedberg; Susanne Kerje; Hamza Babiker; Staffan Svärd; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cross-mating; fitness; microsatellite haplotypes; mosquito infectivity; Infectious diseases; Infektionssjukdomar; Molekylär genetik; Molecular Genetics;

    Sammanfattning : Drug resistance is a major obstacle to management and control of malaria and currently progressing at a rapid rate across Africa. This thesis has examined factors influencing evolution of resistant P. falciparum at two sites in Africa, including parasite migration, cross mating and fitness cost of resistance. LÄS MER

  4. 23. Spatial patterns in the interaction between Salix triandra and associated parasites

    Författare :Lena Niemi; Anders Wennström; Lars Ericson; Keith Clay; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Gonioctena linnaeana; host-parasite interactions; leaf beetle; local adaptation; Melampsora amygdalinae; phenolics; pathogens; plant host; secondary chemistry; Terrestrial ecology; Terrestisk ekologi;

    Sammanfattning : This thesis focuses on mechanisms and processes underlying spatial patterns of resistance and virulence and on local adaptations in plant–parasite interactions. The model system used comprises the plant host Salix triandra, the pathogenic rust fungus Melampsora amygdalinae, the leaf beetle Gonioctena linnaeana, and the galler Pontania triandrae. LÄS MER

  5. 24. Molecular basis for the mechanism of action and resistance to artemisinin combination therapy in Plasmodium falciparum

    Författare :Pedro Ferreira; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Plasmodium falciparum;

    Sammanfattning : Malaria, caused by the Plasmodium falciparum parasite, remains a leading cause of death among children in Africa. To improve treatment efficacy and delay development and spread of antimalarial drug resistance artemisinin artemisinin-based combination therapy (ACT) is now globally recommended as first-line treatment of uncomplicated P. LÄS MER

  7. 25. Ascaridia galli in laying hens: Adaptation of a targeted treatment strategy with attention to anthelmintic resistance

    Författare :Behdad Tarbiat; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Ascaridia galli is a round-worm of wild and domesticated fowl in the Ascaridiidae family within phylum Nematoda. The direct life cycle includes free-living parasite eggs in the environment and larvae and adults worms in the small intestine of the host. Infection is associated with reduced health and production losses in laying hens. LÄS MER