Sökning: "parasite resistance"

Visar resultat 16 - 20 av 56 avhandlingar innehållade orden parasite resistance.

  1. 16. From field to genetics : anthelmintic resistance in the equine roundworm Parascaris univalens

    Författare :Frida Martin; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : The equine roundworm Parascaris univalens is a common parasite of foals. Most foals show mild clinical symptoms, but large worm burdens can lead to severe colic and even death. Regular treatment with anthelmintic drugs has resulted in resistance development, mainly to ivermectin but also to pyrantel and fenbendazole in sporadic cases. LÄS MER

  3. 17. Role of PfATP6 and pfMRP1 in Plasmodium falciparum resistance to antimalarial drugs

    Författare :Sabina Dahlström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Half of the world's population live at risk for malaria and nearly one million people die from the disease every year. The malaria burden is greatest in children and pregnant women in sub-Saharan Africa. LÄS MER

  4. 18. Plasmodium falciparum resistance to amodiaquine in monotherapy and in combination therapy with artesunate

    Författare :Gabrielle Holmgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In response to the increasing resistance to antimalarial monotherapies, artemisinin basedcombination therapy (ACT) is now recommended as first line therapy against uncomplicatedPlasmodium falciparum malaria. However, the choice of partner drug to artemisinin (ART) iscritical for ACT efficacy to endure. LÄS MER

  5. 19. Molecular diagnosis of drug resistance in Plasmodium falciparum and virulence factors in Entamoeba histolytica

    Författare :Sherwan Zindrou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Plasmodium falciparum; dhfr gene; pyrimethamine; cycloguanil; mutations; Polymerase chain reaction; Entamoeba histolytica; hemolysins; hemolysis; virulence factors.;

    Sammanfattning : Four species of the protozoan parasite genus Plasmodium are known to infect man. Plasmodium falciparum, the most virulent species is increasingly associated with resistance to antimalarial drugs. LÄS MER

  7. 20. Malaria on islands : human and parasite diversities and implications for malaria control in Vanuatu

    Författare :Akira Kaneko; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :malaria; Plasmodium falciparum; Plasmodium vivax; glucose-6-phosphate dehydrogenase deficiency; CYP2C19; dihydrofolate reductase; cycloguanil; proguanil; mass drug administration; diversity; island; Vanuatu; Pacific;

    Sammanfattning : The genetic diversities displayed by human and malaria parasites at different frequencies in different geographical areas represent a major obstacle for the development of malaria control strategies including malaria chemotherapy and malaria vaccine. We investigated some genetic diversities on Vanuatu islands with various malaria endemicities. LÄS MER