Sökning: "parasite clearance"

Visar resultat 16 - 20 av 22 avhandlingar innehållade orden parasite clearance.

  1. 16. Antigenic variation in Plasmodium falciparum : understanding the RIFIN protein family

    Författare :Nicolas Joannin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : RIFIN proteins are variable surface antigens, which have a central role in the survival and virulence of the malaria parasite Plasmodium falciparum. Antigenic variation is a mean for these parasites to avoid clearance by the host s immune system. However, this is often a secondary function to the main role of these proteins. LÄS MER

  3. 17. Novel treatment of African trypanosomiasis

    Författare :Suman Kumar Vodnala; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human African Trypanosomiasis (HAT) or Sleeping Sickness is fatal if untreated. Current drugs used for the treatment of HAT have difficult treatment regimens and unacceptable toxicity related issues. LÄS MER

  4. 18. Genetic analysis of murine malaria

    Författare :Susana Campino; Dan Holmberg; Nils Lycke; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Malaria; genetic analysis; Plasmodium; wild derived inbred strains; loci; cerebral malaria; hyperparasitaemia.; Genetik; Clinical genetics; Klinisk genetik; genetik; Genetics;

    Sammanfattning : Malaria, an infectious disease caused by Plasmodium parasites, is one of the major world-scale health problems. Despite the efforts aimed at finding an effective way to control the disease, the success has been thwarted by the emergence of parasite drug resistance and mosquito resistance to insecticides. LÄS MER

  5. 19. Serglycin-dependent mast cell-specific proteases and their potential interactions with Giardia intestinalis

    Författare :Zhiqiang Li; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Mast cells are located in mucosal and connective tissues throughout the body where they play important roles in immune reactions towards infections. Mast cell deficiency results in failure of clearance of the non-invasive intestinal protozoan parasite Giardia intestinalis in mice, but the mast cell-driven mechanisms remain poorly understood. LÄS MER

  7. 20. Host responses to malaria and bacterial co-­infections

    Författare :Maria Nelson; Johan Normark; Sven Bergström; Anna Fahlgren; Olle Stendahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Plasmodium; Malaria; Borrelia; S. pneumoniae; Co-infection; Immunology; Metabolomics;

    Sammanfattning : The two main causes of child mortality and morbidity in Africa are malaria and invasive bacterial diseases. In addition, co-infections in sub-Saharan Africa are the rule rather than the exception. However, not much is known about the host-pathogen interaction during a concomitant infection or how it affects the outcome of disease. LÄS MER