Sökning: "pankreas insulin"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden pankreas insulin.

  1. 1. Mechanisms of insulin exocytosis and release

    Författare :Sebastian Barg; Islet cell physiology; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ClC-3; electrophyiology; confocal microscopy; calcium channel; readily releasable pool; exocytosis; insulin; diabetes; green fluorescent protein; Physiology; Fysiologi;

    Sammanfattning : Endocrine cells as well as neurons release their hormones and transmitters by regulated exocytosis. In the pancreatic B-cell, stimuli like glucose initiate biochemical and electrical processes that culminate in influx of Ca2+, which then triggers exocytosis of insulin-containing granules. LÄS MER

  3. 2. Pathogenesis of type 2 diabetes -role of defects in insulin secretion and insulin sensitivity

    Författare :Devjit Tripathy; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; sekretion; diabetologi; Endocrinology; secreting systems; Calpain 10 gene; genetics of type 2 diabetes; MODY; Endogenous glucose production; Disposition index; Botnia clamp; IGT; IFG; HOMA; insulin sensitivity; insulin secretion;

    Sammanfattning : Type 2 diabetes is characterised by defects in insulin sensitivity, insulin secretion and increased endogenous glucose production. The relative contribution of each of these defects remains controversial. LÄS MER

  4. 3. Regulation of Islet Function by the Neuropeptide PACAP

    Författare :Karin Filipsson; Diabetes - molekylär metabolism; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; postprandial; calcium; sodium; cAMP; intracellular signaling; glucagon; insulin; Pituitary adenylate cyclase-activating polypeptide; PACAP receptors; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : It is known that parasympathetic, sympathetic and sensory nerves innervate the islets and that these nerves harbor both classical neurotransmitters and neuropeptides. However, the neural influence on islet hormone release is complex and not yet fully understood A recently discovered pancreatic neuropeptide is pituitary adenylate cyclase-activating polypeptide (PACAP). LÄS MER

  5. 4. Expression and Regulation of Neuropeptide Y (NPY) in the Islets of Langerhans

    Författare :Ulrika Myrsén Axcrona; Neuroendokrin cellbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; regulatory peptides; diabetes; glucocorticoids; beta cell; islet hormones; neuropeptide Y; insulin; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : This thesis deals with the expression, localization and regulation of neuropeptide Y (NPY) in the pancreatic islets of Langerhans under normal and experimental conditions. NPY is widely distributed in the mammalian nervous system and belongs to a family of closely related petides also comprising peptide YY (PYY) and pancreatic polypeptide (PP). LÄS MER

  7. 5. Regulation of the exocrine pancreas in growing pigs, with special emphasis on entero-pancreatic reflexes

    Författare :Lena Evilevitch; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; kidney bean lectin; Animal physiology; Djurfysiologi; duodenum; entero-pancreatic reflex; insulin; lipas; amylas; trypsin; weaning; development; maturation; inhibition; CCK-receptors; Exocrine pancreas; CCK; pig;

    Sammanfattning : The regulation of the exocrine pancreas has been under thorough investigation for many decades. In rats, cholecystokinin (CCK) is considered to be the major gut hormone stimulating the pancreas to releasing the digestive enzymes. LÄS MER