Sökning: "pancreatic islet transplantation"
Visar resultat 11 - 15 av 42 avhandlingar innehållade orden pancreatic islet transplantation.
11. Exploration of Conditions Affecting Cytokine Production in Experimental Type 1 Diabetes Mellitus
Sammanfattning : Cytokines are soluble signalling mediators within the immune system, and have been shown to be of importance in the development of type 1 diabetes (T1D). This thesis studied the production of cytokines in experimental models of T1D and during transplantation of insulin-producing islets of Langerhans. LÄS MER
12. Challenges in Islet Transplantation and Strategies to Improve Beta-Cell Function
Sammanfattning : The incidence of type 1 diabetes is increasing worldwide and therapies of islet transplantation and potential cell-based therapies are rapidly evolving. Choosing the optimal site for such therapies is crucial for safety and for obtaining the best possible outcome. LÄS MER
13. Influence of Islet-derived Factors in Islet Microcirculation and Endocrine Function
Sammanfattning : Diabetes mellitus is a disorder with complex pathology and is frequently associated with vascular complications. In the islet micro milieu locally generated factors may affect both the physiology and the morphology of the tissue. LÄS MER
14. Implantation-Site Dependent Differences in Engraftment and Function of Transplanted Pancreatic Islets
Sammanfattning : Transplanting pancreatic islets into the liver through the portal vein is currently the most common procedure in clinical islet transplantations for treating patients with brittle type 1 diabetes. However, most islet grafts fail within a 5-year period necessitating retransplantation. LÄS MER
15. Characterizing the pancreatic "isletome" : 3D optical imaging to study diabetes
Sammanfattning : The pancreas is a specialised multipurpose organ, that can be separated into two major compartments: endocrine and exocrine. The exocrine part makes up the majority of the organ volume and functions to secrete digestive enzymes into the small intestine. LÄS MER