Sökning: "pancreatic cancer"

Visar resultat 6 - 10 av 155 avhandlingar innehållade orden pancreatic cancer.

  1. 6. Adenovirus for Cancer Therapy : With a Focus on its Surface Modification

    Författare :Di Yu; Magnus Essand; Dirk Nettelbeck; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; cancer; therapy; neuroblastoma; neuroendocrine; modification; Tat; PTD; cell penetrating peptide; Helicobacter pylori; NAP; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Klinisk virologi; Clinical Virology; Medical Virology; Medicinsk virologi; Molekylär medicin; Molecular Medicine; Molekylär bioteknik; Molecular Biotechnology;

    Sammanfattning : Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy. However, its infectivity is highly dependent on the expression level of coxsackievirus-adenovirus receptor (CAR) on the surface of tumor cells. LÄS MER

  3. 7. Complementary and alternative medicine in cancer : from utilization to a randomized controlled trial

    Författare :Kathrin Wode; Per Fransson; Roger Henriksson; Lena Sharp; Johanna Hök Nordberg; Vinjar Magne Fønnebø; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; epidemiology; evidence-based medicine; neoplasms; pancreatic neoplasms; adult; integrative oncology; complementary therapies; treatment refusal; communication; physician-patient relations; mistletoe; palliative care; quality of life; cross-sectional studies; qualitative research; randomized controlled trial; Sweden; Europe; medicin; Medicine;

    Sammanfattning : Background: Complementary and alternative medicine (CAM) are non-conventional health care approaches used in parallel with or instead of conventional medicine. Little is known about Swedish patients’ patterns of complementary CAM use in the context of cancer. LÄS MER

  4. 8. Pancreatic Cancer. Experimental and Clinical Studies

    Författare :David Ljungman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic neoplasms; Proteasome inhibitors; Apoptosis; Intracellular signaling peptides and proteins; Epidermal growth factor receptor; Pancreaticoduodenectomy; Cost and cost analysis; Quality-adjusted life years; Copy number variations; Comparative genomic hybridization;

    Sammanfattning : Background: Pancreatic cancer is one of the most lethal of known cancers and the only treatment with possibility of cure is surgery. The costs associated with treatment of pancreatic cancer are reputably high, both in terms of morbidity and financially. LÄS MER

  5. 9. Preclinical evaluation of immunostimulatory gene therapy for pancreatic cancer

    Författare :Emma Eriksson; Angelica Loskog; Tanja de Gruijl; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic cancer; immunotherapy; oncolytic viruses; adenoviruses; CD40L; 4-1BBL; IL-6; tumor microenvironment; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : Pancreatic cancer is characterized by its desmoplastic tumor microenvironment and the infiltration of immunosuppressive cells. It is a devastating disease where most patients are diagnosed at a late stage and the treatment options are few. The development of new treatments is surly needed. LÄS MER

  7. 10. Immunosuppressive and metastasis-promoting matrisome proteins in pancreatic cancer : the role of galectin 4 and SERPINB5

    Författare :Tommy Lidström; Daniel Öhlund; Håkan Hedman; Ola Billing; Andreas Lundqvist; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic cancer; galectin 4; immunotherapy; SERPINB5; metastasis; extracellular matrix; drug target; Oncology; onkologi; immunologi; Immunology; Medicine; medicin;

    Sammanfattning : In Sweden 1200-1300 people are diagnosed with pancreatic ductal adenocarcinoma (PDAC) every year. Late diagnosis, together with poor treatment response and resistance to checkpoint inhibitor immunotherapy, contributes to the poor prognosis of the disease. LÄS MER