Sökning: "pancreatic b-cell"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden pancreatic b-cell.

  1. 1. Regulation of growth of the pancreatic B-cell : an experimental study in the rat

    Författare :Ingemar Swenne; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 2. Experimental diabetes mellitus in the mouse : a study of the action of streptozotocin on the pancreatic B-cell

    Författare :Stellan Sandler; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 3. B cell deviations and type 1 diabetes in the NOD mouse

    Författare :Mia Sundström; Kristina Lejon; Susanna Cardell; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Type 1 diabetes; Autoimmunity; NOD mouse; Idd; TACI; Immune response; Immune complex; immunologi; Immunology;

    Sammanfattning : Type 1 diabetes (T1D) is a chronic autoimmune disease in which the insulin producing β-cells in the pancreatic islets of Langerhans are selectively attacked by the immune system. The β-cells are destroyed resulting in a reduced or eliminated insulin production, which in turn lead to a high blood glucose level. LÄS MER

  5. 4. Function of the pancreatic B-cell in spontaneous and experimentally induced diabetes mellitus in mice

    Författare :Rolf Gunnarsson; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  7. 5. The genetic basis of T and B cell contribution to autoimmune diabetes in NOD mice

    Författare :Vinícius Motta; Dan Holmberg; Linda Wicker; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 Diabetes; NOD mouse; CTLA-4; superantigen; T cells; Idd; marginal zone B cells; embryo aggregation chimera; negative selection; Immunogenetics; Immungenetik;

    Sammanfattning : The nonobese diabetic mouse (NOD) is an excellent animal model to study type 1 diabetes. As with some humans, disease in the NOD mouse is effected by a combination of genetic and environmental factors. At least 20 insulin dependent diabetes (Idd) susceptibility loci have been identified so far, both in humans and in the NOD mouse. LÄS MER