Sökning: "palladium-catalyzed reactions"

Visar resultat 1 - 5 av 49 avhandlingar innehållade orden palladium-catalyzed reactions.

  1. 1. New Methods for the Synthesis of Vicinal Stereocenters : Palladium-Catalyzed Domino Reactions and Asymmetric Transfer Hydrogenation

    Författare :Brinton Seashore-Ludlow; Somfai Peter; Kevin Booker-Milburn; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; asymmetric synthesis; domino reactions; palladium-catalyzed reactions; oxindoles; amino alcohols;

    Sammanfattning : In this thesis the synthesis of vicinal stereocenters is investigated in two distinct contexts, namely the construction of 3,3-disubstituted oxindoles and the synthesis of b-hydroxy-a-amino acids. Both scaffolds are prevalent in a range of natural products and biologically relevant compounds and, therefore, methods for their synthesis are of great import. LÄS MER

  2. 2. New Methods for the Synthesis of 3-Substituted 1-Indanones : A Palladium-Catalyzed Approach

    Författare :Anna Arefalk; Anders Hallberg; Mats Larhed; Juan Carlos Carretero; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Heck; palladium; indanone; annulation; microwave heating; triflate; sulfinyl imine; HIV-1 protease inhibitor; Organisk kemi; Organic chemistry; Organisk kemi;

    Sammanfattning : In medicinal chemistry, there is a constant need for new preparative methods, both to make the synthesis process more effective, and to increase the accessibility to a wide variety of compounds. A number of different approaches can be used to attain these goals. LÄS MER

  3. 3. Regio-controlled and fast intermolecular heck reactions : palladium-catalyzed coupling reactions with microwave heating

    Författare :Mats Larhed; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Sammanfattning : .... LÄS MER

  4. 4. Palladium-Catalyzed Carbonylation and Arylation Reactions

    Författare :Jonas Sävmarker; Mats Larhed; Gary Molander; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; palladium; carbonylation; styrene; amidine; aryl ketones; aryl sulfinates; ESI-MS; aryltrifluoroborates; Organic Pharmaceutical Chemistry; Organisk farmaceutisk kemi;

    Sammanfattning : Palladium-catalyzed reactions have found widespread use in contemporary organic chemistry due to their impressive range of functional group tolerance and high chemo- and regioselectivity. The pioneering contributions to the development of the Pd-catalyzed C-C bond forming cross-coupling reaction were rewarded with the Nobel Prize in Chemistry in 2010. LÄS MER

  5. 5. Palladium catalyzed reactions involving -allyl intermediates : preparative and mechanistic aspects

    Författare :Kenneth Granberg; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER