Sökning: "palladacycle"

Hittade 4 avhandlingar innehållade ordet palladacycle.

  1. 1. Asymmetric Catalysis : Ligand Design and Conformational Studies

    Författare :Kristina Hallman; KTH; []
    Nyckelord :asymmetric catalysis; chiral ligand; oxazolines; conformational study; allylic substitution; polymer-bound ligands; dendritic ligands; crown ether; oxidations; palladacycle;

    Sammanfattning : This thesis deals with the design of ligands for efficientasymmetric catalysis and studies of the conformation of theligands in the catalytically active complexes. All ligandsdeveloped contain chiral oxazoline heterocycles. LÄS MER

  3. 2. Fast Microwave-Enhanced Intra-, Pseudo-intra- and Intermolecular Heck Reactions

    Författare :Andreas Svennebring; Mats Larhed; Anja Sandström; Erik Van der Eycken; Uppsala universitet; []
    Nyckelord :Pharmaceutical chemistry; palladium; Heck reaction; chelation control; microwave; Farmaceutisk kemi;

    Sammanfattning : The Heck reaction is one of the most appreciated methods for carbon-carbon bond formation. Due to its mildness and ability to be tuned by additives, it often leaves few alternative competitive reactions. It has also proven easy to develop the reaction conditions in an environmentally benign direction. LÄS MER

  4. 3. Transition Metal Mediated Transformations of Carboranes

    Författare :Ludvig Eriksson; Kalman Szabo; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; carborane; isoquinoline; PK11195; peripheral bensodiazepine receptor; Cu I Iodide; iodinated carborane; palladium; isotopic exchange; Herrmann’s Catalyst; Heck reaction; Suzuki-Miyaura reaction; cross coupling; arylation; olefination; 125-iodine; radiolabelling; carboraneboronic ester; BNCT; 2-iodo-; Kemi; Chemistry; Kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis describes the use of copper and palladium to mediate transformations of carboranes, especially p-carborane.1-(1-p-carboranyl)-N-methyl-N-(2-butyl)-3-isoquinolinecarboxamide, a carborane containing analogue of the peripheral benzodiazepine receptor (PBR) ligand PK11195, has been synthesised. LÄS MER

  5. 4. Heck Reactions with Aryl Chlorides : Studies of Regio- and Stereoselectivity

    Författare :Gopal K. Datta; Mats Larhed; Anders Hallberg; Martin Oestreich; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heck reaction; aryl chloride; vinyl ether; regioselective; stereoselective; palladium; chelation control; microwave; Pharmaceutical chemistry; Farmaceutisk kemi;

    Sammanfattning : Homogeneous palladium-catalyzed Heck vinylation of aryl chlorides was investigated under air using Herrmann’s palladacycle and the P(t-Bu)3-liberating salt [(t-Bu)3PH]BF4. Based on the results, controlled microwave heating was utilized to accelerate model Heck reactions with aryl chlorides down to 30 min employing an electron-poor olefin and a mixture of an ionic liquid and 1,4-dioxane as solvent. LÄS MER