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Visar resultat 1 - 5 av 50 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Unilateral Cleft Lip and Palate : Speech, Voice and Nasal Function in Adults

    Författare :Staffan Morén; Maria Mani; Mats Holmström; Per-åke Lindestad; Göran Laurell; Magnus Becker; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adult; Cleft Lip; Cleft Palate; Cross-Sectional Studies; Control Groups; Dysphonia; Follow-Up Studies; Humans; Nasal Obstruction; Nose Deformities; Otolaryngology; Quality of Life; Reconstructive Surgical Procedures methods; Retrospective Studies; Treatment Outcome; Voice Quality; Acoustic; Oto-Rhino-Laryngology; Oto-rhino-laryngologi;

    Sammanfattning : Cleft lip and palate (CLP) is the most common craniofacial malformation. Even after repair of the cleft there may be persistent symptoms affecting speech, voice, nasal breathing, dentition, appearance and quality of life. LÄS MER

  2. 2. Cleft Size and Maxillary Arch Dimensions in Unilateral Cleft Lip and Palate and Cleft Palate

    Författare :Erika Reiser; Anna Andlin-Sobocki; Valdemar Skoog; Bengt Gerdin; Arja Heliövaara; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Unilateral cleft lip and palate; cleft palate; cleft size; maxillary arch dimensions; crossbite; facial growth; nasal function; Oral and Maxillofacial Surgery; Käkkirurgi;

    Sammanfattning : The wide variation in infant maxillary morphology and cleft size of children with unilateral cleft lip and palate (UCLP) and isolated cleft palate (CP) raise concerns about their possible influences on treatment outcome. The studies in this thesis aimed to investigate the relation between cleft size in infancy and crossbite at 5 years of age (Paper I); the impact of primary surgery on cleft size and maxillary arch dimensions from infancy to 5 years of age (Paper II); associations between cleft size, maxillary arch dimensions and facial growth in both UCLP and CP children (Paper III); and, to evaluate the relation between infant cleft size and nasal airway size and function in adults treated for UCLP (Paper IV). LÄS MER

  3. 3. Unilateral Cleft Lip and Palate : Quality of Life and Nasal Form and Function among Adults

    Författare :Maria Mani; Mats Holmström; Valdemar Skoog; Anna Andlin-Sobocki; Magnus Becker; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; unilateral cleft lip and palate; quality of life; SF-36; nasal function; nasal breathing; nasolabial appearance; cleft width; long-term results; Plastic surgery; Plastikkirurgi; Plastikkirurgi; Plastic Surgery;

    Sammanfattning : Unilateral cleft lip and palate (UCLP) is a craniofacial malformation with functional and aesthetical impact on the face and the upper airways. The aims of the current thesis were to evaluate Quality of life (QoL) in adults treated for UCLP  (I), to objectively evaluate nasal form and function and to search for possible differences in residual nasal deformity and impairment of function between patients operated according to one-stage and two-stage palate closure (II) as well as to evaluate the relationship between professional and lay rating and patient satisfaction with nasolabial appearance (III) and to identify factors associated with lower levels of QoL and less satisfaction with nasal appearance among adults treated for UCLP (IV). LÄS MER

  4. 4. Molecular and Cellular Control of Palate Development in the Mouse

    Författare :Forugh Vazirisani; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cleft palate; fate mapping; Sonic hedgehog; apoptosis; extracellular matrix; mouse;

    Sammanfattning : The formation of a definitive secondary palate in mammals is a multistep process that comprises growth, elevation, contact and fusion of the two palatal shelves. Disruption at any step generates cleft palate, a major congenital birth defect. Therefore, it is important to understand the mechanisms governing normal palate development. LÄS MER

  5. 5. MRI Studies of the Fetal Brain and Cranium

    Författare :Nuno Canto Moreira; Johan Wikström; Raii Raininko; Daniela Prayer; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fetal MRI; Brain; Cranium; Development; Normal; Ear; Lip; Palate; Biometry; Hippocampus; Measurements; Radiology; Radiologi;

    Sammanfattning : Ultrasound is the primary modality for fetal imaging, but Magnetic Resonance Imaging nowadays has a valuable complementary role as it often reveals findings that alter pregnancy management. Knowledge on some clinically relevant areas of the normal fetal development is still lacking, and this was the aim of this project. LÄS MER