Sökning: "paired comparison"

Visar resultat 11 - 15 av 32 avhandlingar innehållade orden paired comparison.

  1. 11. Gene expression in human adipose tissue. Studies of leptin and genes selected by expression profiling

    Författare :Britt Gabrielsson; Göteborgs universitet; []
    Nyckelord :obesity; subcutaneous; omental; DNA microarray; sulfonylurea receptor; fibroblast; growth factors; complement system; fibroblast;

    Sammanfattning : Obesity, and in particular the amount of visceral adipose tissue, is correlated to development of type 2diabetes and cardiovascular disease. The aim of this thesis was to study genes expressed in humanadipose tissue that could be involved in regional adipose tissue homeostasis and/or obesity-associateddisease. LÄS MER

  3. 12. Neuroinflammatory biomarkers in suicidal behavior

    Författare :Josef Isung; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Immune dysregulation is of importance in the pathophysiology underlying psychiatric disorders including major depression, bipolar disorder, and schizophrenia. Neurobiological alterations such as a dysregulated stress-hormonal axis and serotonergic alterations have been reported in suicide attempters at risk for subsequent suicide. LÄS MER

  4. 13. Improving biomarker assessment in breast pathology

    Författare :Stephanie Robertson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The accuracy of prognostic and therapy-predictive biomarker assessment in breast tumours is crucial for management and therapy decision in patients with breast cancer. In this thesis, biomarkers used in clinical practice with emphasise on Ki67 and HER2 were studied using several methods including immunocytochemistry, in situ hybridisation, gene expression assays and digital image analysis, with the overall aim to improve routine biomarker evaluation and clarify the prognostic potential in early breast cancer. LÄS MER

  5. 14. On Transient Noise and its Reduction in Hearing Aids

    Författare :Anders Gingsjö; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; gun shots; sound exposure; speech intelligibility; signal processing; transient reduction; hearing aid; transient noise;

    Sammanfattning : The most important property of a hearing aid is to facilitate verbal communication for hearing impaired people. However, tuning of the acoustical parameters in a hearing aid in order to optimize the speech intelligibility may result in a harsh and unpleasant sound. LÄS MER

  7. 15. Interstitial laser thermotherapy (ILT) of breast cancer - Methodology and immunological responce

    Författare :Kristin Huld-Haraldsdottir; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Laser thermotherapy; Minimally invasive treatment; Tumour immunology; Thermal treatment; Tumour size; Magnetic resonance imaging;

    Sammanfattning : Interstitial laser thermotherapy (ILT) is an attractive form of local therapy against cancer because of its anti-tumor immune activity. The aim of this work was to evaluate ILT in breast cancer with respect to technique, changes in tissue immunocompetent cells and effect on prognosis. LÄS MER