Sökning: "pain mechanism"

Visar resultat 1 - 5 av 97 avhandlingar innehållade orden pain mechanism.

  1. 1. Neuroinflammation and pain

    Författare :Linda Block; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroinflammation; Pain; Persistant pain; Astrocytes; Morphine; Naloxone; Intrathecal administration;

    Sammanfattning : ABSTRACT Background: Persistent pain that remains long after the physiological trigger has been resolved is a disabling condition. A possible mechanism for the transition from acute physiological pain to persistent pain involves low-grade inflammation in the central nervous system, in which inflammatory-activated astrocytes play a significant role. LÄS MER

  3. 2. Chronic Pelvic Pain Persisting after Childbirth : Diagnosis and Implications for Treatment

    Författare :Thomas Torstensson; Per Kristiansson; Margaretha Eriksson; Siv Mørkved; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic pelvic pain; corticosteroid; injection; pain mapping; pelvic pain; physical function; physiotherapy; pregnancy; randomised controlled trial; referred pain; sensitisation; Physiotherapy; Sjukgymnastik fysioterapi;

    Sammanfattning : Objectives: To explore the pain mechanism and the origin of the pain and to evaluate a short-term pain relief treatment in women suffering from CPP persisting after childbirth in order to enable physiotherapeutic intervention.Material and methods: Thirty-six parous women with chronic pelvic pain persisting after childbirth were recruited at the Department of Physiotherapy, SundsvallHospital and by advertisements in newspapers and 29 parous women without chronic pelvic pain were recruited from an organized gynaecological screening at a midwifery surgery. LÄS MER

  4. 3. Interventional pain management focused on zygapophysial joint pain : a health-economic evaluation

    Författare :Johan Hambraeus; Lars Lindholm; Klas-Göran Sahlen; Anni-Maria Pulkki-Brännström; Roine Risto; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic pain; zygapophysial joint; radiofrequency coagulation; patient experience; health related quality of life; QALY; cost-effectiveness; rehabilitation; thematic analysis; empowerment; interventional pain management; rehabiliteringsmedicin; Rehabilitation Medicine; anestesiologi; Anaesthesiology; health services research; hälso- och sjukvårdsforskning;

    Sammanfattning : The pain-system is a central mechanism in our life. Chronic pain is one of the major causes of impaired health-related quality of life according to the World Health Organization’s “Global Burden of Disease”-studies. Zygapophysial joint pain has been shown to account for the pain in 30% - 50% of patients with chronic pain. LÄS MER

  5. 4. Biomarkers for Better Understanding of the Pathophysiology and Treatment of Chronic Pain : Investigations of Human Biofluids

    Författare :Anne-Li Lind; Torsten Gordh; Masood Kamali-Moghaddam; Jonas Bergquist; Eva Kosek; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; chronic pain; neuropathic pain; lumbar radicular pain; amyotrophic lateral sclerosis; radiculopathy; fibromyalgia; pathophysiology; spinal cord stimulation; mechanism of action; disc herniation; cerebrospinal fluid; plasma; biomarker; human; protein; chemokines; cytokines; inflammation; neuroinflammation; mass spectrometry; proximity ligation assay; proximity extension assay; antibody suspension bead array; protein profiling; molecular medicine; personalized medicine; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry; Medicinsk vetenskap; Medical Science; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Chronic pain affects 20 % of the global population, causes suffering, is difficult to treat, and constitutes a large economic burden for society. So far, the characterization of molecular mechanisms of chronic pain-like behaviors in animal models has not translated into effective treatments. LÄS MER

  7. 5. Autonomic reactivity in muscle pain : clinical and experimental assessment

    Författare :Nebojsa Kalezic; Eugene Lyskov; Stein Knardahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autonomic reactivity; stress; chronic pain; experimental pain; back; shoulder; neck; Physiology; Fysiologi; Physiology;

    Sammanfattning : There are numerous indications of possible involvement of the autonomic nervous system in the genesis of chronic pain. The possibility exists that sympathetic activation is related to motor dysfunction and changes in sensory processing, which have otherwise been implicated in musculoskeletal disorders. LÄS MER