Sökning: "p73"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet p73.

  1. 1. p73 in colorectal cancer

    Författare :Daniella Pfeifer; Sun Xiao-Feng; Vladimir Bykov; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Colorectal cancer (CRC) is the third most common cancer in the world, with about 5000 new cases in Sweden every year. CRC is caused by mutation (inherited or acquired) in genes, by gene variants and changed expression of proteins. The primary way to achieve a curative result for CRC is to remove the tumor by surgery. LÄS MER

  3. 2. Molecular studies of radiotherapy and chemotherapy in colorectal cancer

    Författare :Jasmine Evert; Hong Zhang; Xiao-Feng Sun; Karin Jirström; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; Radiotherapy; Chemotherapy; p53; p73; PINCH; miRNAs; Biomedicin; Biomedicine;

    Sammanfattning : .... LÄS MER

  4. 3. Transcriptional Regulation of the Platelet-Derived Growth Factor beta-receptor

    Författare :Anders Hackzell; Göteborgs universitet; []
    Nyckelord :PDGF; cell cycle; p73; p53; SV40; NF-Y; Sp1; Myc;

    Sammanfattning : The Platelet Derived-Growth Factor (PDGF) receptors and ligands are expressed in cells of predominantly mesenchymal origin. Binding of the ligands to the receptors stimulates cell proliferation and other cellular responses such as differentiation and cell movement. LÄS MER

  5. 4. On the structure-function relationship of p73

    Författare :Ulrika Nyman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The development of multicellular organisms requires a balance between the cellular processes of proliferation, differentiation and death. These processes are important throughout the whole life of the organism. Daily, the DNA in our cells is under attack by agents that can cause damage. LÄS MER

  7. 5. p73 : regulator of differentiation and apoptotic cell death

    Författare :Ulrika Nyman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neoplasia is characterized by cells' loss of self-control due to deregulated apoptotic and cell proliferation pathways. Anticancer treatments aim to induce either cell cycle arrest or apoptosis, and these effects are in most part mediated by proteins, like p53 and p73, which are involved in and able to mediate both processes. LÄS MER