Sökning: "p1 60 coactivator"

Hittade 1 avhandling innehållade orden p1 60 coactivator.

1. 1. Molecular mechanisms of estrogen and antiestrogen action

   Författare :Tomas Barkhem; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Estrogen receptor; SHBG; tamoxifen; raloxifene; pS2; p1 60 coactivator; SRC-1; TIF-2;

   Sammanfattning : Estrogen is a key regulatory hormone that affects numerous physiological processes. The estrogen receptors (ER), ER alpha and ER beta, play a central role in mediating the effects of both estrogens and antiestrogens. Estrogen signaling has proven to be multifaceted and the precise mechanism of action remains in many cases elusive. LÄS MER