Sökning: "oxidative stress"

Visar resultat 6 - 10 av 566 avhandlingar innehållade orden oxidative stress.

  1. 6. Molecular mechanism(s) underlying neurodegeneration in SCA7 disease : Role of NOX enzymes and oxidative stress

    Författare :Abiodun Ajayi; Anna-Lena Ström; Ana Cristina Rego; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neurodegeneration; oxidative stress; NOX; metabolism; p53; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Spinocerebellar ataxia type 7 (SCA7) is an autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide expansion in the SCA7 gene resulting in progressive ataxia and retinal dystrophy. SCA7 belongs to a group of neurodegenerative disorders called polyglutamine (polyQ) diseases, that share the common feature of glutamine tract expansions within otherwise unrelated proteins. LÄS MER

  3. 7. Study of molecular mechanism(s) underlying neurodegeneration in SCA7 disease : Role of NOX enzymes and oxidative stress

    Författare :Abiodun Ajayi; Anna-Lena Ström; Boris Zhivotosky; Bengt Mannervik; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neurodegeneration; polyglutamine; oxidative stress; metabolism; NADPH oxidase; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Spinocerebellar ataxia type 7 (SCA7) is an autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide expansion in the SCA7/ATXN7 gene resulting in progressive ataxia and retinal dystrophy. SCA7 belongs to a group of neurodegenerative disorders called polyglutamine (polyQ) diseases, that share the common feature of glutamine tract expansions within otherwise unrelated proteins. LÄS MER

  4. 8. Role of oxidative stress response in radiosensitivity

    Författare :Ali Pour Khavari; Siamak Haghdoost; Bo Stenerlöw; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Oxidative stress; radiosensitivity; 8-oxo-dG; DNA-repair; NRF2; glioblastoma; radiotherapy; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The quality of the ionizing radiation (IR) can be described in terms of its nature, photons or particles, and their corresponding energies. The energy is classified in terms of High or Low linear energy transfer that will produce a different distribution of DNA damage and other molecules in the cell either by direct action or indirect action. LÄS MER

  5. 9. Influence of Oxidative Stress on Muscle and Bone

    Författare :Bengt Östman; Karl Michaëlsson; Lars Nordsletten; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone mineral density; coenzyme Q10; exercise; ischaemia; isprostanes; muscle; oxidative stress; oxygen radicals; reperfusion; tocopherol; Orthopaedics; Ortopedi; ortopedi; Orthopaedics;

    Sammanfattning : Reactive oxygen species (ROS) induce oxidative stress and although are primarily recognized for playing a deleterious biological role, they can be beneficial to cell systems. ROS are extremely short-lived and normally tightly regulated by antioxidant defence systems. LÄS MER

  7. 10. Energy Metabolic Stress Syndrome : Impact of Physical Activity of Different Intensity and Duration

    Författare :Stefan Branth; Leif Hambraeus; Gunnar Ronquist; Mats Stridsberg; Lennart Kaijser; Uppsala universitet; []
    Nyckelord :Medicine; energy; ATP; metabolism; nutrition; body-composition; physical-activity; stress; insulin-resistance; ion-pumps; intracellular swelling and -shrinkage; taurine; reactive oxygen species; Medicin;

    Sammanfattning : All living cell functions require an ongoing supply of energy derived from carbohydrates, lipids and proteins with their own pathways of breakdown. All of them end up in the oxidation of reduced coenzymes, yielding chemically-bound energy in the form of adenosine triphosphate (ATP). LÄS MER