Sökning: "oxidative Heck reaction"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden oxidative Heck reaction.

  1. 1. Novel Metal-Mediated Organic Transformations : Focusing on Microwave Acceleration and the Oxidative Heck Reaction

    Författare :Per-Anders Enquist; Mats Larhed; Anders Hallberg; Troels Skrydstrup; Uppsala universitet; []
    Nyckelord :Organic chemistry; palladium II ; oxidative Heck reaction; high-throughput-chemistry; microwave acceleration; dicobalt octacarbonyl; in situ carbonylation; urea; diaryl ketones; ESI-MS; Organisk kemi;

    Sammanfattning : Transition metals have played an important role in synthetic organic chemistry for more than a century, and offer catalytic transformations that would have been impossible with classical chemistry. One of the most useful and versatile of the transition metals is palladium, which over the years has catalyzed many important carbon-carbon forming reactions. LÄS MER

  3. 2. Palladium(II)-Catalyzed Heck Reactions : Domino Reactions, Decarboxylations, Mechanistic Studies & Continuous Flow Applications

    Författare :Ashkan Fardost; Mats Larhed; Patrick Guiry; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; palladium II ; dft; reaction mechanisms; esi-ms; heck; decarboxylation; microwave; continuous flow;

    Sammanfattning : This thesis describes research efforts dedicated to the development of palladium(II)-catalyzed oxidative Heck and Heck/Suzuki domino reactions, and the applications of a new microwave heating technology, purpose-built for continuous flow in organic synthesis.Paper I describes the development of a ligand-modulated approach for attaching aryl groups to a chelating vinyl ether. LÄS MER

  4. 3. Fast Microwave-Enhanced Intra-, Pseudo-intra- and Intermolecular Heck Reactions

    Författare :Andreas Svennebring; Mats Larhed; Anja Sandström; Erik Van der Eycken; Uppsala universitet; []
    Nyckelord :Pharmaceutical chemistry; palladium; Heck reaction; chelation control; microwave; Farmaceutisk kemi;

    Sammanfattning : The Heck reaction is one of the most appreciated methods for carbon-carbon bond formation. Due to its mildness and ability to be tuned by additives, it often leaves few alternative competitive reactions. It has also proven easy to develop the reaction conditions in an environmentally benign direction. LÄS MER

  5. 4. Mechanistic investigation of platinum and palladium catalysed cross- coupling reactions. Implications for the Stille and Heck reactions

    Författare :Patrik Nilsson; Kemiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metallorganisk kemi; Organometallic chemistry; Oorganisk kemi; Inorganic chemistry; parameter fitting; numerical solutions; platinum II ; palladium II ; NMR spectroscopy; transmetallation; Heck; Stille; kinetics; mechanism;

    Sammanfattning : The present thesis deals with various types of palladium(II) and platinum(II) complexes and their use in homogeneous catalysis. The focus has been devoted to mechanistic investigations concerning the Stille and Heck reactions and studies under both catalytic and stoichiometric conditions were conducted. LÄS MER

  7. 5. Selectivity in Palladium- and Enzyme-Catalyzed Reactions : Focusing on Enhancement of Reactivity

    Författare :Peter Nilsson; Anders Hallberg; Mats Larhed; Matthias Beller; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Palladium; Heck; PCR; Microwaves; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

    Sammanfattning : Catalysis has a profound impact on all living species on the earth. Nature’s catalysts, the enzymes, have the ability to selectively promote a specific bio-chemical transformation, given the required substrate. LÄS MER