Sökning: "oxLDL"

Visar resultat 16 - 20 av 41 avhandlingar innehållade ordet oxLDL.

  1. 16. Nutritional and dysmetabolic factors with potential impact on type 2 diabetes : epidemiological and molecular studies

    Författare :Tina Wirström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 2 Diabetes;

    Sammanfattning : Diabetes is a group of diseases characterized by hyperglycaemia. Type 2 diabetes encompasses 85-95% of all diabetes with a prevalence that is expected to increase worldwide. LÄS MER

  3. 17. Atherosclerosis in middle-aged men. A prospective study with focus on factors related to the metabolic syndrome

    Författare :Karin Wallenfeldt; Göteborgs universitet; []
    Nyckelord :apolipoproteins; atherosclerosis; C-reactive protein; insulin resistance; intima-media thickness; LDL cholesterol; longitudinal study; metabolic syndrome X; smokeless tobacco; ultrasonography;

    Sammanfattning : The metabolic syndrome (MetS) is a clustering of cardiovascular disease CVD) risk factors. Pro-spective studies have demonstrated that patients with MetS are about three times more likely to experience CVD events than those without MetS. Up to one third of the adult population seems to be affected worldwide. LÄS MER

  4. 18. Immune mechanisms in atherosclerosis

    Författare :Ejaz Ahmed; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :atherosclerosis; diabetes; stroke; rheumatoid arthritis; autoantibodies; anticardiolipin; oxidized LDL; hypercholesterolernia; IFN-gamma TNF-alpha IL-1beta IL-1Ra.;

    Sammanfattning : Atherosclerosis is a multifactorial chronic inflammatory disorder. Humoral immune factors as anticardiolipin antibodies (aCL), anti-oxLDL antibodies, circulating immune complexes (CICs), and proinflammatory cytokines such as IFN-gamma, TNF-alpha and EL-1beta have been implicated in atherogenesis. LÄS MER

  5. 19. Immune mechanisms in atherosclerosis : the role of T cells in murine models of atherosclerosis

    Författare :Xinghua Zhou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :atherosclerosis; inflammation; murine models; low density lipoprotein; lipoprotein oxidation; T lymphocyte; T-cell antigen receptors; hypercholesterolemia; autoantibodies; T-cell cytokines; immunization; cardiolipin;

    Sammanfattning : Atherosclerosis is an inflammatory disease. Much interest has been focused on the immune responses in the pathogenesis of the disease. The role of T cells in the development of atherosclerosis was therefore investigated in murine models in this study. LÄS MER

  7. 20. Monocyte chemoattractant protein-1 and CC-chemokine receptor-2 in two different conditions related to atherosclerosis

    Författare :Henrik Blomqvist; Linköpings universitet; []
    Nyckelord :atherosclerosis; hypercholesterolaemia; coronary artery disease; inflammation; MCP-1; CCR2; CRP; MEDICINE; MEDICIN;

    Sammanfattning : Atherosclerosis is the leading cause of death in the industrialized parts of the world. The pathological process is characterised by increased lipid influx to the arterial wall due to elevated circulating levels of low density lipoprotein (LDL). LDL is oxidatively modified by reactive oxygen species forming oxLDL. LÄS MER