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Visar resultat 1 - 5 av 41 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Macrophage expression of VEGF and VEGFR-1. Potential involvement in atherogenesis

    Författare :Linda Salomonsson; Göteborgs universitet; []
    Nyckelord :atherosclerosis; macrophages; oxLDL; statins; VEGF; VEGFR-1;

    Sammanfattning : The vascular endothelial growth factor (VEGF) family is a group of proteins which contributes to both neovascularisation and inflammation. Elevated levels of VEGF have been found in subjects with atherosclerosis and correlate to several cardiovascular risk factors, e.g. hypertension and hyperlipidemia. LÄS MER

  3. 2. Effect of Ischaemia-Reperfusion on Rabbit Kidney and Human Brain

    Författare :Jagdish Shivlal Gondalia; Göteborgs universitet; []
    Nyckelord :Free radicals; ischaemia-reperfusion; cell bioenergetics; NMR; ESR; carotid artery stenosis; endarterectomy; allopurinol; acetylcysteine; MMP-1; ICAM-1; MCP-9; oxLDL;

    Sammanfattning : Free radicals are produced in various organs at ischaemia-reperfusion. The final stage in radical damage is lipid peroxidation. We have demonstrated previously that a lipid-soluble antioxidant improves restoration of bioenergetics in rabbit kidneys after ischaemia, as reflected in 31P spectrometry. LÄS MER

  4. 3. Carotid stenosis: aspects on progression, stabilization and follow-up

    Författare :Giuseppe Asciutto; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; carotid plaque; echogenity; beta-blockers; inflammation; antibodies anti oxLDL;

    Sammanfattning : Cardiovascular (CV) atherosclerotic diseases are the leading cause of death in Western nations. The presence of a carotid plaque, the degree of carotid stenosis as well as the rate of progression of carotid disease has been shown to be independent predictive factors for future ischemic events. LÄS MER

  5. 4. Cellular immunity and inflammation in atherosclerosis

    Författare :Dirk Marcus Wuttge; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Atherosclerosis; T cell; oxLDL; malondialdehyde; hapten; posttranslational; interleukin-] 5; retinoic acid receptor; inflammation;

    Sammanfattning : Atherosclerosis, the major cause of death and disability in western countries, is nowadays recognized as an inflammatory disease. Low density lipoprotein (LDL), the major carrier of cholesterol in plasma, is trapped in the subendothelial space, where compounds inside of LDL are chemically modified through lipid peroxidation. LÄS MER

  7. 5. Nutritional status, body composition and diet in patients with rheumatoid arthritis

    Författare :Ann-Charlotte Elkan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Rheumatoid arthritis; rheumatoid cachexia; body composition; fat-free mass; fat-free mass index; nutritional questionnaires; body mass index; dyslipidemia; oxLDL; anti-phosphorylcholine;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory disease with higher mortality rate than in the general population, which is largely attributed to cardiovascular disease (CVD). Another consequence of the inflammatory process is change in body composition with decreased muscle mass and increased fat mass. LÄS MER