Sökning: "osteosarcoma"

Visar resultat 21 - 25 av 34 avhandlingar innehållade ordet osteosarcoma.

  1. 21. Investigation of antiviral and anticancer nucleoside analog substrate recognition of drosophila melanogaster and herpes virus deoxyribonucleoside kinases

    Författare :Nicola Solaroli; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The deoxyribonucleoside kinase of the fruit fly Drosophila melanogaster (Dm-dNK) is a multisubstrate enzyme that phosphorylates pyrimidine and purine deoxyribonucleosides as well as several anticancer and antiviral nucleoside analogs. Dm-dNK is sequence related to the human deoxycytidine kinase (dCK), deoxyguanosine kinase (dGK) and thymidine kinase 2 (M), as well as to the herpes simplex virus type-1 thymidine kinase (Hsv-1 TK). LÄS MER

  3. 22. Expression and regulation of steroid metabolizing enzymes in cells of the nervous and skeletal systems : Special focus on vitamin D metabolism

    Författare :Mokhtar Almokhtar; Maria Norlin; Kjell Wikvall; Gösta Eggertsen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Little is known about the mechanisms of vitamin D actions in the brain and bone. In this study, the metabolism of vitamin D and its regulation in various cell cultures of the nervous and skeletal systems were examined. LÄS MER

  4. 23. Polyomavirus infections in humans

    Författare :Annika Lundstig; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Polyomaviruses; tumour virology; BK virus; neuroblastoma; maternal infection; Real Time PCR; enzyme immunoassay; seroprevalence; JC virus; SV40; virus like particles VLPs ; seroepidemiology; biobank; mesothelioma tissues; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : The human polyomaviruses BKV and JCV are endemic and infect > 70% of population worldwide. Primary infections occur during childhood and are largely subclinical. Following primary infection, both viruses persist as latent infections in the kidneys and B lymphocytes. LÄS MER

  5. 24. Effects of silicon on bone. Clinical observations and experimental cell studies

    Författare :Catarina Magnusson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; silicon; osteoclast; pregnancy; lactation; bone metabolism; bone regeneration;

    Sammanfattning : Bone health has a major impact on life quality. In Sweden, osteoporosis is a highly prevalent skeletal disease that primarily affects the elderly, causing fragility fractures and pain. LÄS MER

  7. 25. Effects of 1,25-dihydroxyvitamin D3 and growth hormone on osteoblast-like cells

    Författare :Orlando Morales; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Vitamin D3; Growth Hormone; Osteoblasts; signal transduction;

    Sammanfattning : Bone remodeling, which occurs throughout life in both cancellous and cortical bone, involves mainly the osteoblasts and osteoclasts. The osteoblast is responsible for the production of matrix, which later becomes mineralized. The osteoclast is a large, multinuclear cell, which is responsible for bone resorption. LÄS MER