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Visar resultat 1 - 5 av 26 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Kalciumbrist - osteoporos : parathyreoideaes roll vid adaptionen till lågt kalciumintag hos vuxna råttor

   Författare :Olof Ahlgren; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : .... LÄS MER

3. 2. Hälsofrämjande frakturprevention vid osteoporos : Kraft till förändring

   Författare :Viktoria Helene Hjalmarson; Margaretha Strandmark K; Margareta Möller; Lillemor Lundin-Olsson; Karlstads universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; frakturprevention; osteoporos; motivation; empowerment; salutogenesis implementering; hälsopromotion; Grounded theory; fallstudie samt hierarkisk klusteranalys; Public Health Science; Folkhälsovetenskap;

   Sammanfattning : .... LÄS MER

4. 3. Altered body composition in adults with complex congenital heart disease

   Författare :Karna Johansson; Camilla Sandberg; Bengt Johansson; Thomas Mooe; Mats Börjesson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adults with complex congenital heart disease; ACHD; body composition; skeletal muscle; lean mass; muscular strength; sarcopenia; bone; bone mass; bone mineral density; bone health; osteoporosis; fat; fat mass; obesity; Vuxna med medfödda hjärtfel; vuxna med komplexa medfödda hjärtfel; komplexa medfödda hjärtfel; kroppssammansättning; skelettmuskel; styrka; sarkopeni; ben; benmassa; bendensitet; osteoporos; fett; fettmassa; obesitas; kardiologi; Cardiology;

   Sammanfattning : Introduction: Thanks to achievements in paediatric heart surgery and medicine, the population of adults with surgically repaired or palliated congenital heart defects is growing. Many of these adults have reduced exercise capacity, weaker muscular strength and shorter height, all of which suggest an altered body composition. LÄS MER

5. 4. Pharmacometric Models for Individualisation of Warfarin in Adults and Children

   Författare :Anna-Karin Hamberg; Mia Wadelius; E Niclas Jonsson; Lena E Friberg; Jeffrey S Barrett; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; warfarin; pharmacokinetics; pharmacodynamics; pharmacometrics; pharmacogenetics; dose individualisation; children; Klinisk farmakologi; Clinical Pharmacology;

   Sammanfattning : Warfarin is one of the most widely used anticoagulants. Therapy is complicated by warfarin’s narrow therapeutic range and pronounced variability in individual dose requirements. Although warfarin therapy is uncommon in children, it is crucial for children with certain congenital or acquired heart diseases. LÄS MER

7. 5. Clinical Pharmacogenetics of Olanzapine : with Focus on FMO Gene Polymorphisms

   Författare :Mao Mao Söderberg; Marja-Liisa Dahl; Maria Gabriella Scordo; Inger Johansson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; olanzapine; pharmacogenetics; drug metabolism; schizophrenia; therapeutic drug monitoring; FMO1; FMO3; CYP1A2; UGT1A4; Clinical Pharmacology; Klinisk farmakologi;

   Sammanfattning : Pharmacogenetics is the study of variability in drug response attributed to genetic variation. Olanzapine (OLA) is a widely used antipsychotic drug for schizophrenia treatment. The pharmacokinetics of OLA display large inter-individual variation leading to multiple-fold differences in drug exposure between patients at a given dose. LÄS MER