Sökning: "osteoclast"

Visar resultat 11 - 15 av 54 avhandlingar innehållade ordet osteoclast.

  1. 11. Antibody- and osteoclast-dependent mechanisms of chronic pain

    Författare :Alexandra Jurczak; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic pain is a frequent condition that affects approximately 20% of worldwide population with a higher prevalence among women. Due to the lack of optimal treatment, chronic pain leads to decreased life quality as well as significant physical and psychological complications. LÄS MER

  3. 12. Peri-implantitis : treatment and effects of enamel matrix derivative

    Författare :Catrine Isehed; Pernilla Lundberg; Anders Holmlund; Leif Jansson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; implant; peri-implantitis; bone regeneration; enamel matrix derivative; surgical treatment; proteome; bone marrow macrophages; osteoclast formation; bone resorption; odontologi; Odontology;

    Sammanfattning : Biological complications affecting osseointegrated dental implants are a growing treatment problem in clinical practice. Since the number of implant carriers has increased in recent decades, this is an urgent topic in dentistry. LÄS MER

  4. 13. The calcitonin gene family of peptides : receptor expression and effects on bone cells

    Författare :Susanne Granholm; Ulf Lerner; Pernilla Lundberg; Göran Andersson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; CT family of peptides; osteoclast differentiation; bone resorption; CTR; CRLR; RAMPs; Cell biology; Cellbiologi;

    Sammanfattning : The calcitonin gene family of peptides consists of calcitonin (CT), two calcitonin gene related peptides (α-CGRP, β-CGRP), adrenomedullin (ADM), amylin (AMY), three calcitonin receptor activating peptides (CRSP1-3) and intermedin/adrenomedullin2 (IMD). These peptides bind to one of two G protein -coupled receptors, the calcitonin receptor (CTR) or the calcitonin receptor-like receptor (CRLR). LÄS MER

  5. 14. Tissue responses to bone-implant biomaterials

    Författare :Haihong Liao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Gene expression; interface; mineralization; nacre; osteoblast; osteoclast; titanium;

    Sammanfattning : The purpose of the studies was to understand the mechanisms which underlie the interaction between tissue and bone-implant biomaterials. Tissue and naturally occurring aragonite nacre interaction was systematically studied for the first time by combined histological examination, cellular and molecular biological approaches. LÄS MER

  7. 15. Matrix resorption in endochondral bone growth : ultrastructural studies, with special attention to the chondroclast

    Författare :Joakim Nordahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :chondroclast; osteoclast; cartilage resorption; TRAP; cathepsin K; fibronectin; bone sialoprotein; osteopontin;

    Sammanfattning : A substantial amount of the calcified cartilage in the distal parts of the epiphyseal plate is resorbed during endochondral growth of long bones. However, the mechanisms involved in this process are still largely unknown. On the other hand, bone-resorption in the lower metaphysis has been thoroughly investigated. LÄS MER