Sökning: "osteocalcin"

Visar resultat 6 - 10 av 31 avhandlingar innehållade ordet osteocalcin.

  1. 6. Healing of endosseous implants with different surface characteristics in grafted and non-grafted bone : clinical and experimental studies

    Författare :Måns Jungner; Stefan Lundgren; Malou Hultcrantz; Carina Lundqvist; Peter Nilsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dental implants; surface characteristics; bone graft; maxillary sinus; implant survival; oxidized surface; turned surface; sinus membrane elevation; bone formation; macrophages; osteocalcin; osteopontin; CD68; odontologi; Odontology;

    Sammanfattning : Aims: This study uses radiological and clinical evaluations of the healing of endosseous titanium implants presented with different surface characteristics in the clinical situation (paper I-III) and experimentally to describe the early bone healing in maxillary sinus membrane elevation with and without the use of grafting material (paper IV).Material and methods: In paper I, 136 patients were treated with 394 dental implants – 199 were oxidized titanium implants (Nobel Biocare TiUnite) and 195 were turned titanium surface implants (Nobel Biocare Mark III). LÄS MER

  3. 7. Mechanism of conditional repression of human osteocalcin gene activity by glucocorticoids

    Författare :Thomas Meyer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :glucocorticoid receptor; osteocalcin; gene regulation; TATA box element;

    Sammanfattning : Bone is one of the major target sites of steroid hormone action. Steroid hormones like cortisol, vitamin D and estradiol are responsible for principle events associated with bone formation and resorption. LÄS MER

  4. 8. Experimental studies on the effects of insulin-like growth factor I and glucocorticoids on bone metabolism

    Författare :Kenneth B. Jonsson; Uppsala universitet; []
    Nyckelord :Medical sciences; Bone; bone resorption; glucocorticoids; insulin-like growth factor I; osteoblasts; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Osteoporosis is a major cause of disability among patients that are dependent on glucocorticoids in the treatment of inflammatory disease. The pathogenesis behind this side effect is complex, involving dysregulation of hormonal systems and direct effects on bone cells. LÄS MER

  5. 9. Bone density, bone geometry and bone development in young men - the importance of pubertal timing and fracture history

    Författare :Anna Darelid; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peak bone mass; bone mineral density; bone development; fracture; young adulthood; men;

    Sammanfattning : Background and objective: Peak bone mass, the maximal bone mass attained in young adulthood, is an important factor of the lifetime risk of developing osteoporosis. The aim of this thesis was to study the development of bone mineral density (BMD) and bone geometry around the time of peak bone mass in men, and also to investigate the association between pubertal timing, fracture history, bone turnover markers and BMD and bone geometry in young men. LÄS MER

  7. 10. Early-life metal exposure and child growth and development

    Författare :Annachiara Malin Igra; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cadmium, lead and arsenic are toxic metals, the exposure to which occurs primarily through food and drinking water. While many studies are available about their health effects in adults, studies in children and adolescents are more limited, especially for cadmium. LÄS MER