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Visar resultat 1 - 5 av 65 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Nanoscale Osseointegration : Characterization of Biomaterials and their Interfaces with Electron Tomography

   Författare :Kathryn Grandfield; Håkan Engqvist; Peter Thomsen; Anders Palmquist; Alexandra Porter; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Electron tomography; transmission electron microscopy; hydroxyapatite; titanium; titania; bone; implant; osseointegration; interface; mesoporous; Materialvetenskap; Materials Science;

   Sammanfattning : Bone response is one of the key determining factors in the overall success of biomaterials intended for bone regeneration and osseointegration. Understanding the formation of bone at an implant surface may lead to the improved design of biomaterials for the future. LÄS MER

3. 2. Aspects of oral implant technology and osseointegration

   Författare :Rainde Naiara Rezende de Jesus; Malmö universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomaterials; oral implants; surface topography; surface roughness; surface energy; surface wettability; hydrophilicity; macrogeometry; implant body; thread design; surgical protocol; oversized drilling; osseointegration; bone-to-implant contact; bone density; primary implant stability; insertion torque; removal torque; removal energy; connection stiffness; osteoclasts; RAW264.7 cells; gene expression;

   Sammanfattning : Behandling med käkbensförankrade tandimplantat är en vanlig metod för att ersätta förlorade tänder hos helt och partiellt tandlösa patienter. Trots att implantatbehandling uppvisar en långsiktigt hög lyckande- och överlevnadsfrekvens (90–95% efter 10 år) så förekommer implantatförluster och marginal benförlust kring implantaten under det första året efter insättning och/eller belastning, vilket kan försämra det estetiska resultatet. LÄS MER

4. 3. On osseointegration in response to controlled surface nanotopography

   Författare :Dimitrios Karazisis; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; in vivo; nanotopography; osseointegration; topography;

   Sammanfattning : Knowledge about the biological responses provoked by the surface modification of titanium implants on the nanoscale is still in its infancy. Although in vitro studies claim superior effects considering higher adhesion and proliferation of osteoblasts in the short term and even differentiation towards the osteogenic cell lineage in the long term, these responses do not necessarily reflect the actual outcome in the complex in vivo environment. LÄS MER

5. 4. Mechanisms of Osseointegration: Experimental Studies on Early Cellular and Molecular Events in vivo

   Författare :Omar Omar; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Osseointegration; titanium; bone; gene expression; bone-implant interface; qPCR; inflammation; cytokine; chemotaxis; chemokine; integrin; bone formation; remodeling; in vivo; rat; immunohistochemistry; ultrastructure; biomechanical torque test;

   Sammanfattning : The early cellular and molecular activities determining the early tissue response and bone formation at bone/implant interface are not fully understood. The general aim of the current thesis was to develop a model for studying the early molecular and cellular activities in different bone types, and in response to different implant surface properties. LÄS MER

7. 5. The synergistic role of hierarchical macro- and mesoporous implant surface and microscopic view of enhanced osseointegration

   Författare :Guang Han; Zhijian Shen; Anders Palmqvist; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Porosity; cell adhesion; cell proliferation; surface topography; implant; bone-implant interface; argon ion beam polishing; osteogenesis; osseointegration; Materials Chemistry; materialkemi;

   Sammanfattning : The trend for designing of a titanium implant explored using different chemical compositions and crystallinity materials until people realized that the implant surface character was another important factor affecting the rate and extent of osseointegartion. Titanium received a macroporous titania surface layer by anodization, which contains open pores with average pore diameter around 5μm. LÄS MER