Sökning: "orthopaedic implants"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden orthopaedic implants.

  1. 1. Fixation of Spinal Implants : Clinical and Experimental Studies on the Effects of Hydroxyapatite Coating

    Författare :Bengt Sandén; Acke Ohlin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Hydroxyapatite; pedicle screw; histomorphometry; fixation; radiolucent zones; screw loosening; Kirurgi; Surgery; Kirurgi; Orthopaedics; ortopedi;

    Sammanfattning : Loosening of implants is a frequent complication in orthopaedic surgery. The aim of this thesis was to evaluate hydroxyapatite coating of pedicle screws with mechanical and histological methods and to correlate the results with the radiological findings.Hydroxyapatite (HA) coating of pedicle screws was investigated in experimental studies in sheep. LÄS MER

  3. 2. Experimental implant-associated orthopaedic infections

    Författare :Åke Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Osteomyelitis; anaerobic bacteria; implant design and material; bacterial collagen- and fibronectin-binding;

    Sammanfattning : Although indispensable in today's medicine, orthopaedic implants may also cause adverse reactions. A foreign body increases the local susceptibility to colonisation by microorganisms, and hence the risk of infections. These infections are rare, but many result in prolonged or permanent impairment. LÄS MER

  4. 3. Improved titanium and steel implants : Studies on bisphosphonate, strontium and surface treatments

    Författare :Paula Linderbäck; Pentti Tengvall; Per Aspenberg; Håkan Engqvist; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : Purpose: The general aim of this thesis was to increase the understanding of biomaterial surface modifications and local delivery of osteoporosis drugs for bone integration. We therefore (i) characterised and investigated model surface coatings for controlled drug delivery in a rat tibia screw model (ii) elucidated the effect of surface treatment for activation of complement system in vitro. LÄS MER

  5. 4. On component integration in total hip arthroplasty. Pre-clinical evaluation

    Författare :Warren Macdonald; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Total hip arthroplasty; orthopaedic implants; implant design; biomechanical testing; in vitro evaluation; titanium; zirconia; polyethylene; surgical accuracy;

    Sammanfattning : .... LÄS MER

  7. 5. On the pathogenesis of infections associated with percutaneous osseointegrated orthopaedic implants

    Författare :Magdalena Zaborowska; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; osseointegration; amputation prosthesis; implant-associated infection; biofilm; staphylococci; extracellular vesicles; host defence; cytokines; cell death;

    Sammanfattning : Orthopaedic implants enable the restitution of locomotor function and improve the quality of life of many people. However, biomaterial-associated infection may occur due to the propensity of microorganisms to adhere and colonize implant surfaces. LÄS MER