Sökning: "orthogonal affinity purification"

Hittade 2 avhandlingar innehållade orden orthogonal affinity purification.

  1. 1. An albumin-binding domain as a scaffold for bispecific affinity proteins

    Författare :Johan Nilvebrant; Sophia Hober; Andrew Bradbury; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; albumin-binding domain; bispecific; albumin; affinity protein; phage display; staphylococcal display; orthogonal affinity purification; TNF-alpha; ErbB2; ErbB3; SRA - Molekylär biovetenskap; SRA - Molecular Bioscience;

    Sammanfattning : Protein engineering and in vitro selection systems are powerful methods to generate binding proteins. In nature, antibodies are the primary affinity proteins and their usefulness has led to a widespread use both in basic and applied research. LÄS MER

  2. 2. Interaction engineered three-helix bundle domains for protein recovery and detection

    Detta är en avhandling från Stockholm : KTH

    Författare :Tove Alm; Sophia Hober; Rainer Hahn; [2010]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ABD; Zbasic; albumin; protein engineering; phage display; staphylococcal display; inclusion bodies; refolding; proteomics; orthogonal affinity purification; TECHNOLOGY Bioengineering; TEKNIKVETENSKAP Bioteknik; TECHNOLOGY Bioengineering Immunology engineering; TEKNIKVETENSKAP Bioteknik Immunteknik;

    Sammanfattning : HTML clipboard The great advances in DNA technology, e.g. sequencing and recombinant DNA techniques, have given us the genetic information and the tools needed to effectively produce recombinant proteins. Recombinant proteins are valuable means in biotechnological applications and are also emerging as alternatives in therapeutic applications. LÄS MER