Sökning: "orosomucoid low"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden orosomucoid low.

  1. 1. Properties of the endothelial cells and the glomerular barrier

    Författare :Jenny Sörensson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Capillary permeability; kidney glomerulus physiology; isolated perfused kidney; endothelium; orosomucoid; charge; horseradish peroxidase; inflammation; proteoglycan; cAMP.;

    Sammanfattning : The kidneys are vital organs that filter plasma to produce 180 liters of primary urine per day. Only 1% of this volume is excreted and the rest is reabsorbed. Naturally, such huge amounts of fluid must be well controlled to maintain the homeostasis, which is a prerequisite for life. LÄS MER

  2. 2. Physiological and morphological aspects of the glomerular barrier in health and disease. Results based on experimental studies in the rat

    Författare :Clara Hjalmarsson; Göteborgs universitet; []
    Nyckelord :glomerular permeability; isolated perfused kidney; charge; endothelial surface layer; glycocalyx; electron microscopy; orosomucoid; nephrotic syndrome; proteinuria;

    Sammanfattning : Tremendous amounts of fluid are filtered every day through the kidneys. The anastomosing capillary loops surrounded by Bowman s capsule, forming the glomerulus, function in accordance with the interplay between the hydrostatic and the colloid osmotic pressure. The result of the action of these mechanisms is the production of primary urine. LÄS MER

  3. 3. C-reactive protein in clinical practice with special regard to infectious diseases

    Författare :Lars-Olof Hansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :CRP; general practice; septi-caemia; endocarditis; influenza; bacterialmeningitis; viral meningitis; community-acquired pneumonia; malignant melanoma; albumin; transferrin; a-1 anti-trypsin; hapto-globin; orosomucoid; transthyretin; iron.;

    Sammanfattning : A new simple affinity purification method for human CRP using Arginine-Sepharose 4B was developed with a recovery of >90 % and containing < 5-10 % contaminating proteins. In a multicenter study including 607 consecutive patients in general practice, erythrocyte sedimentation rate (ESR) and serum CRP were compared. LÄS MER

  4. 4. Homocysteine and Coronary Artery Disease With special Reference to Biochemical Effects Of Vitamin Therapy

    Författare :Torfi Jonasson; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; pyridoxine.; oxidative stress; lipid peroxidation; inflammation; homocysteine; endothelial function; folate; F2-isoprostanes; cystatine C; Acut coronary syndrome; cardiovascular disease; asymmetric dimethylarginine; cobalamine;

    Sammanfattning : An elevated plasma level of homocysteine has been suggested as a risk factor for cardiovascular disease. The objectives of this thesis were to study the influence of renal function on homocysteine levels in patients with coronary artery disease and to explore the association of elevated plasma levels of homocysteine to oxidative stress, inflammation, and endothelial dysfunction. LÄS MER

  5. 5. Novel risk factors for atrial fibrillation in an urban population

    Författare :Samuel Adamsson Eryd; Kardiovaskulär forskning - epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ceruloplasmin; atrial fibrillation; epidemiology; genetic polymorphisms; intima-media thickness; plasma proteins; red blood cell distribution width; risk factors;

    Sammanfattning : Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in the general population, and a major cause of morbidity and mortality. Low-grade inflammation, erythrocyte volume variation, and subclinical atherosclerosis have repeatedly been associated with cardiovascular disease, but it remains unclear whether these risk factors are also associated with incident AF. LÄS MER