Sökning: "opioid growth factor"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden opioid growth factor.
1. The effects of growth hormone on opioid-induced toxicity in vitro
Sammanfattning : There is an ongoing opioid crisis in the United States that is portrayed by a large number of opioid-related deaths. Many of these cases involve commonly used prescription opioids, such as morphine, oxycodone, fentanyl, and methadone. This is concerning and highlights the problems associated with long-term opioid treatment. LÄS MER
2. Growth Hormone and Anabolic Androgenic Steroids : Effects on Neurochemistry and Cognition
Sammanfattning : Growth hormone (GH) stimulates growth and metabolism but also displays profound effects on the central nervous system (CNS). GH affects neurogenesis and neuroprotection, and has been shown to counteract drug-induced apoptosis in the brain. LÄS MER
3. Evolution of the Neuropeptide Y and Opioid Systems and their Genomic Regions
Sammanfattning : Two whole genome duplications (2R) occurred early in vertebrate evolution. By using combined information from phylogenetic analyses and chromosomal location of genes, this thesis delineates the evolutionary history of two receptor-ligand systems that expanded by these large scale events. LÄS MER
4. The Impact of Growth Hormone and Gamma-Hydroxybutyrate (GHB) on Systems Related to Cognition
Sammanfattning : Drug dependence is a serious and increasing problem in our society, especially among adolescents. The use of the large variety of substances available can result in a range of physiological and psychological adverse effects on individuals and negative consequences on the society overall. LÄS MER
5. CNS Targets for GH and IGF-1 : Emphasis on Their Regulation in Relation to Cognitive Processes
Sammanfattning : The interest for the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and its role in the central nervous system (CNS) has grown during the past decade. GH has been associated with psychological functions as sleep, mood, general well-being and learning and memory. LÄS MER