Sökning: "onkologi 2010"

Visar resultat 1 - 5 av 43 avhandlingar innehållade orden onkologi 2010.

  1. 1. Evaluation of the effectiveness of mammography screening in Northern Sweden

    Författare :Pál Bordás; Per Lenner; Håkan Jonsson; Lennarth Nyström; Edward Azavedo; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mammography; screening; sensitivity; interval cancer; survival; mortality; Oncology; Onkologi; onkologi; Oncology;

    Sammanfattning : Service screening with mammography was implemented in Northern Sweden between 1989 and 1998, covering 190,000 women aged 40-74 years constituting the target population in the area. The aim of this thesis was the evaluation of mammography screening in Northern Sweden with special focus on selected screening performance indicators and on the disease outcome. LÄS MER

  3. 2. Radiolabeled acetate PET in oncology imaging : studies on head and neck cancer, prostate cancer and normal distribution

    Författare :Aijun Sun; Jens Sörensen; Silvia Johansson; Mikael Karlsson; Katrine Åhlström Riklund; Ingela Turesson; Heikki Minn; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 11C-acetate; 18F-fluoroacetate; PET; head and neck cancer; staging; delineating tumor volume; clearance rate; perfusion; RT; treatment outcome; benign and malignant lymph node; prostate cancer; normal distribution; Oncology; Onkologi; onkologi; Oncology;

    Sammanfattning : The use of positron emission tomography (PET) for imaging in oncology has grown rapidly in recent years. 2-[18F]-fluorodeoxyglucose (FDG) is the most common tracer of PET, although drawbacks exist. LÄS MER

  4. 3. ASNA1 and cisplatin resistance : studies in C. elegans and in human tumor cells

    Författare :Oskar Hemmingsson; Peter Naredi; Mef Nilbert; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ASNA1; Cisplatin; C. elegans; Drug resistance; Apoptosis; Surgery; Kirurgi; Oncology; Onkologi; Surgery; kirurgi; Oncology; onkologi; cellforskning; cell research;

    Sammanfattning : Platinum based chemotherapy is widely used to treat cancer. Cisplatin (diamminedichloroplatinum) combination treatments provide cure for metastatic testicular cancer and prolong survival for patients suffering from ovarian, head and neck, bladder and non small cell lung cancer. LÄS MER

  5. 4. Establishment and characterization of a murine T-cell lymphoma/leukemia model

    Författare :Ann-Sofie Johansson; Dan Holmberg; Magnus Lindskog; Finn Skou Pedersen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mouse model; T-cell lymphoma; Moloney murine leukemia virus; proviral integration; lymphomagenesis; COX-2; omega 3; Oncology; Onkologi; onkologi; Oncology;

    Sammanfattning : Mouse models of human disease are valuable tools for studying pathogenesis and for evaluating novel therapies. T-cell lymphoma is a relatively rare disease in humans, affecting 100-150 persons yearly in Sweden. It exists in both aggressive and more indolent forms. LÄS MER

  7. 5. Molecular Radionuclide Imaging Using Site-specifically Labelled Recombinant Affibody Molecules : Preparation and Preclinical Evaluation

    Författare :Sara Ahlgren; Vladimir Tolmachev; Anna Orlova; Göran Hedenstierna; Joachim Feldwisch; Raymond Reilly; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molecular radionuclide imaging; Affibody molecules; HER2; cancer detection; radiolabelling; technetium; indium; cobalt; SPECT; PET; Oncology; Onkologi; Diagnostic radiology; Diagnostisk radiologi; Radiation biology; Strålningsbiologi; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Radionuclide molecular imaging is an emerging multidisciplinary technique that is used in modern medicine to visualise diseases at cellular and molecular levels. This thesis is based on five papers (I-V) and focuses on the development of site-specific radiolabelled recombinant anti-HER2 Affibody molecules and preclinical evaluations in vitro and in vivo of the labelled conjugates. LÄS MER