Sökning: "one-pot peptide coupling and intramolecular Michael addition"

Hittade 1 avhandling innehållade orden one-pot peptide coupling and intramolecular Michael addition.

  1. 1. GALIELLALACTONE ANALOGUES – SYNTHESIS AND PROPERTIES

    Författare :Ritha Gidlöf; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Galiellalactone; one-pot peptide coupling and intramolecular Michael addition; tandem palladium-catalyzed carbonylation intramolecular Diels-Alder; STAT3 inhibition;

    Sammanfattning : Cancer cells use normal cell signalling pathways in a proliferative fashion in order to prolong their own survival. Inhibition of one of the major signal proteins, STAT3 (Signal Transducer and Activator of Transcription 3) has previously been shown to induce apoptosis. LÄS MER