Sökning: "on-line sample"

Visar resultat 16 - 20 av 75 avhandlingar innehållade orden on-line sample.

1. 16. Individualized leukapheresis of hematopoietic cells for cellular therapies

   Författare :Anna Mårtensson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Leukapheresis; hematopoietic stem cell; CD34; monocyte; on-line sample; prediction;

   Sammanfattning : Hematopoietic stem and progenitor cells from blood (HSC) are collected by leukapheresis from patients after mobilization with G-CSF +/- chemotherapy to be used in autologous transplantation. The established method to measure the content of HSC in peripheral blood and HSC collections is by their expression of the CD34-antigen. LÄS MER

3. 17. Mass Spectrometric Applications for Diagnosing Metabolic and Endocrine Diseases

   Författare :Mark M. Kushnir; Jonas Bergquist; Alan L Rockwood; David Herold; Uppsala universitet; []
   Nyckelord :Analytical chemistry; biomarker; liquid chromatography; tandem mass spectrometry; LC-MS MS; sample preparation; isomers; steroid hormones; congenital adrenal hyperplasia; polycystic ovary syndrome; Analytisk kemi;

   Sammanfattning : Disease-specific compounds (biomarkers) are analyzed in clinical laboratories to assist with diagnosing diseases. This thesis describes development and validation of liquid chromatography tandem mass spectrometry (LC-MS/MS) based tests for diagnosing a diverse group of endocrine and metabolic diseases. LÄS MER

4. 18. Sample Handling Techniques in Biological and Environmental Applications Emphasizing Biomolecular Recognition and MALDI-TOF MS

   Författare :Patrik Önnerfjord; Reumatologi och molekylär skelettbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein identification; microchip IMER; microdispensing; MALDI-TOF MS; fluorescence polarization; flow immunoassay; pesticide immunoassays; phenol biosensor; restricted access media; SPE; Analytical chemistry; Analytisk kemi;

   Sammanfattning : The use of restricted access media and other stationary phases for clean-up and trace enrichment of environmental samples coupled on-line to liquid chromatography using diode array detection as well as thermospray MS is described. This on-line configuration was compared with commercially available ELISAs for the determination of triazines in complex matrices, showing superior precision and accuracy with the chromatographic method. LÄS MER

5. 19. Flow injection systems for process analytical chemistry

   Författare :Ingrid Lukkari; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Flow injection; Sequential injection; Process analytical chemistry; Multivariate calibration; Sensor injection; Gas-diffusion; Sample clean-up;

   Sammanfattning : Flow injection systems have great potential for sample handling and analysis in process analytical chemistry. The flexibility and versatility of flow injection manifolds can he utilized in specific applications of sample conditioning and analysis. LÄS MER

7. 20. Miniaturized, Membrane-Based and Environmentally Green Sample Preparation Systems: Applications for Biological and Environmental Aqueous Samples

   Författare :Thaer Barri; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytisk kemi; Analytical chemistry; Free concentration; Exhustive extraction; Microporous membrane liquid-liqid extraction; Miniaturization; Supported liquid membrane extraction; Environmental chemistry; Miljökemi;

   Sammanfattning : Contemporary advancements in miniaturization of analytical systems have advantageously fostered development, automation, and hyphenation of a variety of sample preparation techniques. Among several downscaled extraction designs, porous synthetic polymeric membranes (such as flat sheet (FS) or hollow fiber (HF)) have been utilized for membrane-based extraction, separating two aqueous phases (as in supported liquid membrane (SLM) extraction or one aqueous phase and another organic phase (as in microporous membrane liquid-liquid extraction (MMLLE)). LÄS MER