Sökning: "on angiogenesis"

Visar resultat 1 - 5 av 322 avhandlingar innehållade orden on angiogenesis.

1. 1. Directing Angiogenesis : Cellular Responses to Gradients in vitro

   Författare :Irmeli Barkefors; Johan Kreuger; Lena Kjellén; Pär Gerwins; Ferdinand Le Noble; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Angiogenesis; Endothelial cell; Cell migration; Chemotaxis; Gradients; Microfluidics; VEGFA; VEGFR2; Exocyst; Exocytosis; Cell and molecular biology; Cell- och molekylärbiologi; Medical Biochemistry; Medicinsk biokemi;

   Sammanfattning : Blood vessels are essential for the delivery of nutrients and oxygen to tissues, as well as for the removal of waste products. Patients with tumors, wounds or diabetes all have active angiogenesis, formation and remodeling of blood vessels, a process that is initiated and manipulated by gradients of secreted signaling proteins. LÄS MER

3. 2. On angiogenesis modulation

   Författare :Mattias Kalén; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : During evolution, the transition from unicellular to multicellular organisms required the origin of a transport system capable of interconnecting specialized cells throughout the body of the organism. In higher animals, this route of transportation is the cardiovascular system, which allows gas exchange, and transport of immune cells, hormones, macromolecules, nutrients and waste products. LÄS MER

4. 3. Regulation of Angiogenesis

   Författare :Helena Larsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; angiogenesis; anti-angiogenesis; endostatin; latent antithrombin; prelatent antithrombin; Crk; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Sammanfattning : Angiogenesis is the formation of new blood vessels from pre-existing ones. New blood vessel formation is fundamental in processes such as reproduction, embryonic development and wound healing. Growth of neoplasms is accompanied by increased angiogenesis. This thesis describes cellular and molecular mechanisms of importance for angiogenesis. LÄS MER

5. 4. Experimental therapies of malignant glioma : with emphasis on angiogenesis inhibition

   Författare :Maria Sandström; Roger Henriksson; Mikael Johansson; Anja Smits; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioma; angiogenesis; VEGF; tyrosinekinaseinhibitor; ZD6474; plasminogenactivator; tPA; uPA; proteomics; Oncology; Onkologi;

   Sammanfattning : Malignant glioma consists of a group of diseases where the localisation and the nature of the disease makes treatment an extreme challenge. Two important biological features of malignant glioma cells are their infiltrative growth and their ability to induce angiogenesis. LÄS MER

7. 5. The Human Endometrium : Studies on Angiogenesis and Endometriosis

   Författare :Christian Moberg; Matts Olovsson; Anneli Stavreus-Evers; Lalit Kumar Parameswaran Grace; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endometrium; angiogenesis; endothelial cell; endometriosis; receptivity; implantation; oestrogen receptor; progesterone receptor; crystallin; interleukin; vasoactive intestinal peptide; peritoneal fluid; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Angiogenesis is thought to play a pivotal role in the cycling endometrium. Coordinated by oestrogen and progesterone, endometrial blood vessel development is primarily mediated by vascular endothelial growth factor-A (VEGF-A), which promotes endothelial cell (EC) proliferation and protects ECs from induced apoptosis. LÄS MER