Sökning: "oligonucleotide"

Visar resultat 16 - 20 av 151 avhandlingar innehållade ordet oligonucleotide.

  1. 16. Oligonucleotide synthesis using the hydrogenphosphonate approach

    Författare :Tor Regberg; Stockholms universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  3. 17. Nucleoside H-phosphonates : chemical studies directed towards oligonucleotide synthesis

    Författare :Roger Strömberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  4. 18. Cell-penetrating peptide based nanocomplexes for oligonucleotide delivery

    Författare :Jakob Regberg; Ülo Langel; Arwyn Tomos Jones; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptides; oligonucleotides; gene therapy; drug delivery; scavenger receptors; blood-brain barrier; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Oligonucleotide-based drugs hold great promise for the treatment of many types of diseases, ranging from genetic disorders to viral infections and cancer. The problem is that efficient delivery across the cell membrane is required for oligonucleotides to have their desired effect. Cell-penetrating peptides (CPPs) provide a solution to this problem. LÄS MER

  5. 19. Pharmaceutical insights into improving oligonucleotide delivery and efficacy

    Författare :Osama Saher; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The power of gene therapy lies in their capacity to target a disease on a genetic level. Nucleic acid containing therapeutics can be utilized to treat, diagnose or prevent a possible disease or condition. However, the successful delivery of such molecules constitutes a major limitation. LÄS MER

  7. 20. DNA detection through oligonucleotide ligation and time-resolved fluorescence

    Författare :Martina Samiotaki; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER